Akyol Furkan Burak, Özdem Tayfun, Varol Mehmet Emin, Demirkıran Tuna, Tokgöz Yiğit, Kubat Emre, Kadan Murat, Karabacak Kubilay
Department of Cardiovascular Surgery, Health Sciences University, Gülhane Training and Research Hospital, Ankara, Türkiye.
Turk Gogus Kalp Damar Cerrahisi Derg. 2024 Dec 31;32(4 Suppl 2):052-53. doi: 10.5606/tgkdc.dergisi.2024.msb-30. eCollection 2024 Nov.
This study aimed to share early- and mid-term results in patients with bicuspid aortic valve (BAV) disease who underwent tricuspidization with the Ozaki procedure. The data of 44 patients (32 males, 12 females; mean age: 51.47±15.18 years) diagnosed with BAV who underwent tricuspidization with the aortic valve neocuspidization technique between February 2019 and July 2024 were retrospectively analyzed.
Additional surgical procedures were performed on 21 (47.72%) patients with BAV morphology. Echocardiographic measurements showed a significant reduction in preoperative peak and mean aortic valve pressures at one and 12 months. In patients who underwent simultaneous surgical procedures, the mean aortic cross-clamp time was 111±29.7 min, and the mean cardiopulmonary bypass time was 153±43.9 min. For isolated BAV defects, the mean aortic cross-clamp and cardiopulmonary bypass times were 89.9 ±19.5 and respectively. During the follow-up period, no patient required mechanical aortic valve replacement. One patient required pacemaker implantation on the seventh postoperative day due to the development of a third-degree atrioventricular block. In one patient, an ischemic cerebrovascular event occurred in the early postoperative period.
Although aortic valve neocuspidization requires experience, the application of standardized procedures allows for successful outcomes in BAV defects through the tricuspidization procedure. The tricuspidization procedure provides a more physiological structure and excellent hemodynamic performance of the aortic valve.
本研究旨在分享接受大崎手术进行三尖瓣化的二叶式主动脉瓣（BAV）疾病患者的早期和中期结果。回顾性分析了2019年2月至2024年7月期间44例诊断为BAV并接受主动脉瓣新瓣叶形成技术三尖瓣化的患者（32例男性，12例女性；平均年龄：51.47±15.18岁）的数据。
21例（47.72%）BAV形态患者接受了额外的外科手术。超声心动图测量显示，术后1个月和12个月时，术前主动脉瓣峰值和平均压力显著降低。在接受同期外科手术的患者中，平均主动脉阻断时间为111±29.7分钟，平均体外循环时间为153±43.9分钟。对于孤立的BAV缺损，平均主动脉阻断时间和体外循环时间分别为89.9±19.5分钟。在随访期间，没有患者需要进行机械主动脉瓣置换。1例患者在术后第7天因发生三度房室传导阻滞需要植入起搏器。1例患者在术后早期发生缺血性脑血管事件。
尽管主动脉瓣新瓣叶形成需要经验，但标准化程序的应用通过三尖瓣化程序可使BAV缺损获得成功结果。三尖瓣化程序可提供更符合生理结构的主动脉瓣和出色的血流动力学性能。
