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无菌性脑膜炎所致梗阻性脑积水可采用内镜下第三脑室造瘘术治疗。

Noncommunicating Hydrocephalus Caused by Aseptic Meningitis Can Be Treated With Endoscopic Third Ventriculostomy.

作者信息

Nitta Ayumu, Sasagawa Yasuo, Nakada Mitsutoshi

机构信息

Department of Neurosurgery, Toyama City Hospital, Toyama-shi, Toyama, 939-8511, Japan.

Department of Neurosurgery, Kanazawa University, Kanazawa, Ishikawa, 920-8641, Japan.

出版信息

J Med Cases. 2025 Apr;16(4):135-139. doi: 10.14740/jmc5109. Epub 2025 Apr 22.

Abstract

Noncommunicating hydrocephalus is a rare complication of aseptic meningitis and is predominantly characterized by the obstruction of cerebrospinal fluid (CSF) absorption. Traditional treatment methods include external ventricular drainage (EVD) and ventriculoperitoneal (VP) shunt. However, endoscopic third ventriculostomy (ETV) might also be effective in the case of aseptic meningitis. A 19-year-old woman presented with fever, lymphadenopathy, and arthritis, followed by headache and vomiting. Magnetic resonance imaging (MRI) showed no hydrocephalus. CSF analysis revealed mild pleocytosis and elevated protein levels, with negative cultures, leading to the diagnosis of aseptic meningitis. After an initial recovery with supportive care, the patient returned a month later with an acute progressive headache and altered consciousness. Computed tomography (CT) revealed lateral and third ventricular enlargement, while MRI showed cerebellar swelling and foraminal adhesions, indicative of obstructive hydrocephalus. ETV was performed through the right anterior horn of the lateral ventricle. Postoperative recovery was uneventful, and the patient remained asymptomatic after steroid treatment. ETV is a viable option for treating noncommunicating hydrocephalus associated with aseptic meningitis, even when CSF malabsorption is present.

摘要

非交通性脑积水是无菌性脑膜炎的一种罕见并发症,主要特征是脑脊液(CSF)吸收受阻。传统治疗方法包括脑室外引流(EVD)和脑室腹腔(VP)分流术。然而,对于无菌性脑膜炎病例,内镜下第三脑室造瘘术(ETV)可能也有效。一名19岁女性出现发热、淋巴结病和关节炎,随后出现头痛和呕吐。磁共振成像(MRI)显示无脑积水。脑脊液分析显示轻度细胞增多和蛋白水平升高,培养结果为阴性,诊断为无菌性脑膜炎。在通过支持治疗初步康复后,患者一个月后因急性进行性头痛和意识改变再次就诊。计算机断层扫描(CT)显示侧脑室和第三脑室扩大,而MRI显示小脑肿胀和孔道粘连,提示梗阻性脑积水。通过侧脑室右前角进行了ETV。术后恢复顺利,患者在接受类固醇治疗后仍无症状。即使存在脑脊液吸收不良,ETV也是治疗与无菌性脑膜炎相关的非交通性脑积水的可行选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fdaf/12045797/444ba13c474d/jmc-16-04-135-g001.jpg

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