Adli Danung Nur, Sholikin Mohammad Miftakhus, Sitaresmi Pradita Iustitia, Ani Nurgiartiningsih Veronica Margareta, Crooijmans Richard P M A
Feed and Animal Nutrition Department, Faculty of Animal Science, Smart Livestock Industry Study Programme, Universitas Brawijaya, Malang, Indonesia.
Research Center for Animal Husbandry, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
J Anim Physiol Anim Nutr (Berl). 2025 May 5. doi: 10.1111/jpn.14123.
Probiotics are increasingly used in poultry nutrition because of their potential to improve performance and reproductive outcomes. However, there is limited consensus on the effectiveness of different probiotic strains and formulations in broiler breeder hens. This meta-analysis aimed to evaluate the impact of various probiotics on broiler breeder performance and reproductive traits. A comprehensive data set on probiotic supplementation in poultry broiler breeder hens (of different strains) was compiled spanning the time period from 1990-2024. The effect size (Hedge's g) of probiotics was analysed to estimate the random and fixed effects of study variations. Among the rooster strains, the Hubbard strain presented a significant reduction in the number of dead sperm (p < 0.01). Moreover, multistrain probiotics were found to be more effective than single strains (p < 0.01). In hens, probiotics were associated with a significantly lower feed conversion ratio (FCR) (p < 0.001), as were improvements in the fertility and hatchability of settable eggs (p < 0.001). In particular, the addition of probiotics derived from Bacillus subtilis significantly increased fertility and hatchability (p < 0.001). In summary, both single-strain and multistrain probiotics significantly increase various reproductive and performance parameters in broiler breeders, with multistrain probiotics consistently showing superior effects across multiple areas. The inclusion of multistrain probiotics up to 1 g/kg generally yielded positive effects on several parameters in broiler breeder hens. These findings support the inclusion of probiotics, particularly multistrain formulations, to increase reproductive efficiency and performance in broiler breeders, providing a sustainable alternative to antibiotics.
由于益生菌具有改善家禽生产性能和繁殖结果的潜力，因此在禽类营养中使用得越来越多。然而，对于不同益生菌菌株和制剂在肉种鸡中的有效性，目前尚未达成广泛共识。本荟萃分析旨在评估各种益生菌对肉种鸡生产性能和繁殖性状的影响。我们汇编了1990年至2024年期间关于（不同菌株的）肉种鸡补充益生菌的综合数据集。分析了益生菌的效应大小（Hedge's g），以估计研究差异的随机效应和固定效应。在公鸡品系中，哈伯德品系的死精数量显著减少（p < 0.01）。此外，发现多菌株益生菌比单菌株益生菌更有效（p < 0.01）。在母鸡中，益生菌与显著更低的饲料转化率（FCR）相关（p < 0.001），可孵化蛋的受精率和孵化率也有所提高（p < 0.001）。特别是，添加枯草芽孢杆菌来源的益生菌显著提高了受精率和孵化率（p < 0.00,1）。总之，单菌株和多菌株益生菌均显著提高了肉种鸡的各种繁殖和生产性能参数，多菌株益生菌在多个方面始终表现出更优的效果。添加高达1 g/kg的多菌株益生菌通常对肉种鸡的多个参数产生积极影响。这些发现支持在肉种鸡中添加益生菌，特别是多菌株制剂，以提高繁殖效率和生产性能，为抗生素提供了一种可持续的替代方案。
