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角膜屈光透镜切除术(KLEx)后的再次治疗:各种方法的结果以及屈光手术委员会(KRC)的建议对再次治疗发生率的影响

[Retreatment after keratorefractive lenticule extraction (KLEx) : Results of various methods and influence of the recommendations of the Committee for Refractive Surgery (KRC) on the incidence of retreatment].

作者信息

Förster Anika, Muqbel Ziad, Alkarkoukly Samer, Dick H Burkhard, Taneri Suphi

机构信息

Zentrum für Refraktive Chirurgie, Augenzentrum am St. Franziskus-Hospital Münster, Hohenzollernring 70, 48145, Münster, Deutschland.

Ruhr-Universität Bochum, Bochum, Deutschland.

出版信息

Ophthalmologie. 2025 May 5. doi: 10.1007/s00347-025-02239-1.

Abstract

BACKGROUND

Keratorefractive lenticule extraction (KLEx) has been shown to be safe and effective for the correction of myopia and myopic astigmatism. Residual refractive errors reduce the uncorrected postoperative visual acuity leading to patient dissatisfaction and increased retreatment rates.

AIM OF THE STUDY

The aim was to assess the potential influence of the recommendations of the Committee for Refractive Surgery (KRC) on the likelihood of retreatment and to compare the results of various methods for retreatment after KLEx for myopia.

METHODS

Retrospective study of eyes with myopia and myopic astigmatism in which KLEx (SMILE, Visumax 500, Carl Zeiss Meditec, Jena, Germany) was performed between April 2015 and December 2022.

RESULTS

A total of 2462 eyes from 1278 patients were analyzed. Of the eyes 3.05% (n = 75) were retreated within 24 months. Eyes in the recommended treatment range (corrections up to -8.0 dpt in the stronger main section) had a 50% lower risk of retreatment than eyes within the borderline range (corrections between -8.0 dpt and -10.0 dpt in the stronger main section). Retreatment was predominantly performed using the advanced surface ablation (ASA n = 44) or the Circle program (transformation of a SMILE cap into a flap, n = 29). The postoperative results of both methods after 3 months were comparably safe and effective; however, visual recovery was significantly faster with Circle. A second KLEx treatment in two eyes (one patient) resulted in a residual refractive error, which impaired the uncorrected visual acuity even 1.7 years later.

CONCLUSION

There was a significantly lower retreatment rate in the recommended treatment range than in the borderline range according to the KRC recommendations. In addition, the ASA and Circle proved to be equally predictable but with different healing processes. These results can help with the education and selection of patients.

摘要

背景

角膜屈光透镜切除术(KLEx)已被证明在矫正近视和近视散光方面是安全有效的。残余屈光不正会降低术后未矫正视力,导致患者不满并增加再次治疗率。

研究目的

本研究旨在评估屈光手术委员会(KRC)的建议对再次治疗可能性的潜在影响,并比较KLEx术后近视的各种再次治疗方法的结果。

方法

对2015年4月至2022年12月期间接受KLEx(SMILE,Visumax 500,德国耶拿卡尔蔡司医疗技术公司)治疗的近视和近视散光眼进行回顾性研究。

结果

共分析了1278例患者的2462只眼。其中3.05%(n = 75)的眼在24个月内接受了再次治疗。处于推荐治疗范围内(较强主子午线方向矫正度数达-8.0 DPT)的眼再次治疗风险比处于临界范围内(较强主子午线方向矫正度数在-8.0 DPT至-10.0 DPT之间)的眼低50%。再次治疗主要采用先进表面切削术(ASA,n = 44)或Circle程序(将SMILE瓣转化为角膜瓣,n = 29)。两种方法术后3个月的结果在安全性和有效性方面相当;然而,Circle程序的视力恢复明显更快。两只眼(一名患者)接受第二次KLEx治疗后出现残余屈光不正,即使在1.7年后仍损害未矫正视力。

结论

根据KRC建议,推荐治疗范围内的再次治疗率明显低于临界范围。此外,ASA和Circle程序在可预测性方面相当,但愈合过程不同。这些结果有助于患者教育和选择。

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