Jiang Zhijian, Zhang Nan, Zhu Maoli, Huang Liang, Dong Jianhong
Department of Ophthalmology, Shanghai Xuhui Central Hospital, Shanghai, 200237, People's Republic of China.
Int Ophthalmol. 2025 May 5;45(1):172. doi: 10.1007/s10792-025-03530-5.
To explore the long-term clinical efficacy of AcrySof toric intraocular lens (IOL) implantation to correct regular corneal astigmatism in cataract patients with axial myopia at primary hospitals.
A total of 78 cataract patients (78 eyes) with regular corneal astigmatism and axial myopia were enrolled in the retrospective cohort study and were divided into two groups according to axial length (AL) (group 1: 24‒27 mm; group 2: 27‒30 mm). Best-corrected visual acuity (BCVA; in logarithms of the minimum angle of resolution), astigmatism value, and the lens axis deviation (LAD) were determined before and at 3 and 12 months after operation.
BCVA (LogMAR) and residual refractive astigmatism (RAS) at 3 and 12 months after IOL implantation were significantly lower than those before implantation in each group (p < 0.05). The differences of LAD at 3 and 12 months between the two groups were not significant (p > 0.05). The proportion of eyes with LAD exceeding 10° at 12 months was significantly lower in group 1 than in group 2 (p = 0.043). AL was closely correlated with LAD (r = 0.360, p = 0.001), and AL (odds ratio 2.527, 95% confidence interval 1.110-5.751) was a significant, independent risk factor for LAD at 12 months.
These data suggested that implantation of an AcrySof toric IOL is effective for correcting regular corneal astigmatism in eyes with axial myopia and cataract at primary hospitals. AL was an independent risk factor for toric IOL rotation.
探讨在基层医院,植入AcrySof散光型人工晶状体(IOL)矫正白内障合并轴性近视患者规则角膜散光的长期临床疗效。
本回顾性队列研究纳入78例患有规则角膜散光和轴性近视的白内障患者(78只眼),根据眼轴长度(AL)分为两组(1组:24 - 27mm;2组:27 - 30mm)。分别于术前及术后3个月和12个月测定最佳矫正视力(BCVA;以最小分辨角的对数表示)、散光值和晶状体轴偏斜(LAD)。
IOL植入术后3个月和12个月时,每组的BCVA(LogMAR)和残余屈光性散光(RAS)均显著低于植入前(p < 0.05)。两组术后3个月和12个月时LAD的差异无统计学意义(p > 0.05)。12个月时LAD超过10°的眼在1组中的比例显著低于2组(p = 0.043)。AL与LAD密切相关(r = 0.360,p = 0.001),且AL(优势比2.527,95%置信区间1.110 - 5.751)是12个月时LAD的显著独立危险因素。
这些数据表明,在基层医院,植入AcrySof散光型IOL矫正轴性近视合并白内障患者的规则角膜散光是有效的。AL是散光型IOL旋转的独立危险因素。