Alohan Daniel I, Chandra Christina, Young Henry N, Quamina Alvan, Holland David P, Crawford Natalie D
Department of Behavioral, Social, and Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.
AIDS Educ Prev. 2025 Apr;37(2):107-125. doi: 10.1521/aeap.2025.37.2.107.
This mixed-methods study explored willingness to use long-acting injectable pre-exposure prophylaxis (LAI-PrEP) among a pharmacy-based sample of men, including sexual and gender minoritized (SGM) individuals. We conducted qualitative interviews ( = 10) with HIV-negative Black men, including Black SGM individuals, and surveys ( = 103) across three study phases with men recruited from community pharmacies in Atlanta, Georgia. Interviews explored perceived benefits and concerns related to LAI-PrEP; surveys assessed willingness and related reasons. Thematic analysis was used for interview transcripts, and descriptive statistics summarized survey responses. Participants mentioned benefits such as improved adherence and reduced stigma, but also noted concerns about medical mistrust and fear of needles. Willingness was higher in the transitional pilot phase than in the pilot phase, where concerns about side effects and comfort were more common. Findings highlight the need for tailored LAI-PrEP strategies that address barriers among Black SGM populations and promote equitable HIV prevention.
这项混合方法研究探讨了在以药房为基础抽取的男性样本（包括性少数群体和性别少数群体[SGM]个体）中使用长效注射暴露前预防药物（LAI-PrEP）的意愿。我们对包括黑人SGM个体在内的HIV阴性黑人男性进行了定性访谈（n = 10），并在三个研究阶段对从佐治亚州亚特兰大社区药房招募的男性进行了调查（n = 103）。访谈探讨了与LAI-PrEP相关的感知益处和担忧；调查评估了意愿及相关原因。对访谈记录进行了主题分析，描述性统计总结了调查回复。参与者提到了诸如提高依从性和减少耻辱感等益处，但也指出了对医疗不信任和害怕打针的担忧。在过渡试点阶段的意愿高于试点阶段，在试点阶段对副作用和舒适度的担忧更为常见。研究结果凸显了制定针对性的LAI-PrEP策略的必要性，这些策略应解决黑人SGM人群中的障碍并促进公平的HIV预防。
