Msomi Nosihle S, Levy Joshua I, Matteson Nathaniel L, Ndlovu Nkosenhle, Ntuli Phindile, Baer Adam, Pilz Dylan, Mabasa Victor, Gwala Sipho, Singh Natasha, Subramoney Kathleen, Phalane Emmanuel, Macheke Mokgaetji, Motloung Mantshali, Mangena Thabo, Monametsi Lethabo, Rabotapi Lebohang, Maposa Sibonginkosi, Birmingham Amanda, Zeller Mark, Karthikeyan Smruthi, De Hoff Peter, Harris Simon, Knight Rob, Laurent Louise C, Andersen Kristian G, McCarthy Kerrigan, Yousif Mukhlid
Centre for Vaccines and Immunology, National Institute for Communicable Diseases, a division of the National Health Laboratory Service, Johannesburg, South Africa.
Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.
PLOS Glob Public Health. 2025 May 5;5(5):e0004443. doi: 10.1371/journal.pgph.0004443. eCollection 2025.
Timely pathogen surveillance and reporting is essential for effective public health guidance. Web dashboards have become a key tool for communicating public health information to stakeholders, health care workers, and the broader community. Over the SARS-CoV-2 pandemic, wastewater surveillance has increasingly been incorporated into public health workflows for outbreak monitoring and response, enabling community-representative and low-cost monitoring to supplement clinical surveillance. However, the methods used for visualization and dissemination of clinical and wastewater surveillance data differ across programs, and best practices are yet to be defined. In this work, we demonstrate data workflows and dashboards used to perform wastewater-based public health surveillance in tandem with clinical data across local and national scales, leveraging custom-built, reproducible, and open-source software. Using a centralized data aggregation and analysis hub approach, we establish multiple data pipelines for data storage, wrangling, and standardized analyses, and deploy custom-built web dashboards that allow for immediate public release. We find that our approach is effective across scales, computing architectures, and dissemination strategies, and provides an adaptable model to incorporate additional pathogens and epidemiological data.
及时的病原体监测和报告对于有效的公共卫生指导至关重要。网络仪表盘已成为向利益相关者、医护人员和更广泛社区传达公共卫生信息的关键工具。在新冠疫情期间,废水监测越来越多地被纳入公共卫生工作流程,用于疫情监测和应对,从而实现具有社区代表性且低成本的监测,以补充临床监测。然而,不同项目用于临床和废水监测数据可视化及传播的方法各不相同,最佳实践尚未明确。在这项工作中,我们展示了用于在地方和国家层面将基于废水的公共卫生监测与临床数据协同进行的数据工作流程和仪表盘,利用定制的、可重复的和开源软件。通过采用集中式数据聚合和分析中心方法,我们建立了多个用于数据存储、整理和标准化分析的数据管道,并部署了允许立即公开发布的定制网络仪表盘。我们发现我们的方法在不同规模、计算架构和传播策略上均有效,并提供了一个可适应的模型,以纳入其他病原体和流行病学数据。