年龄依赖性氨基糖苷类肾毒性。
Age-dependent aminoglycoside nephrotoxicity.
作者信息
Fujita K, Sayama T, Abe S, Murayama T, Tashiro H
出版信息
J Urol. 1985 Sep;134(3):596-7. doi: 10.1016/s0022-5347(17)47308-3.
PMID:4032563
Abstract
Urinary N-acetyl-beta-D-glucosaminidase activity was examined in 41 patients who received a 5-day course of aminoglycoside. Both pretreatment N-acetyl-beta-D-glucosaminidase values and the increase in N-acetyl-beta-D-glucosaminidase after treatment were high in elderly groups, suggesting the increased vulnerability of the kidney with aging.
摘要
对41例接受了为期5天氨基糖苷类药物治疗的患者的尿N-乙酰-β-D-氨基葡萄糖苷酶活性进行了检测。老年组治疗前的N-乙酰-β-D-氨基葡萄糖苷酶值以及治疗后该酶的升高均较高，提示随着年龄增长肾脏易损性增加。
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