Nadeem Zain Ali, Rehman Obaid Ur, Akram Umar, Iftikhar Muhammad Ali, Irfan Hamza, Fatima Eeshal, Imran Hiba, Hurjkaliani Sonia, Khan Alishba
Allama Iqbal Medical College, Lahore, Pakistan.
Services Institute of Medical Sciences, Lahore, Pakistan.
Sleep Med. 2025 Aug;132:106552. doi: 10.1016/j.sleep.2025.106552. Epub 2025 May 2.
Children with cerebral palsy (CwCP) often struggle with sleep issues, which has a serious negative influence on their general health and quality of life. There are insufficient data on the prevalence of various sleep disorders, even though recognising and treating them is vital.
Determining the prevalence of sleep disorders in CwCP is the primary objective of this systematic review and meta-analysis.
An electronic search was conducted on MEDLINE, Embase, Scopus, ScienceDirect, and Web of Science for all relevant articles using pre-specified eligibility criteria. Pooled proportions of CwCP having sleep problems were calculated in a random effects model using R version 4.3.2.
The updated systematic review and meta-analysis included 42 studies. The Sleep Disturbance Scale for Children (SDSC) showed abnormal scores in 26 % (95 % CI: 17 %-37 %) of children with CP. Subscale abnormalities included disorders of initiation and maintenance of sleep (28 %), sleep breathing disorders (17 %), excessive somnolence (12 %), sleep hyperhidrosis (10 %), and sleep-wake transition disorders (19 %). The Paediatric Sleep Questionnaire (PSQ) indicated abnormal scores in 39 % (95 % CI: 6 %-80 %) of children. Sensitivity analyses confirmed these findings, though some publication bias was noted in the PSQ outcome.
About a quarter of CwCP have experienced sleep problems, which may deteriorate their quality of life. In order to improve the quality of life for CwCP, regular sleep examinations and focused therapies are necessary.
脑瘫患儿（CwCP）常常面临睡眠问题，这对他们的整体健康和生活质量产生严重负面影响。尽管认识并治疗各种睡眠障碍至关重要，但关于其患病率的数据并不充分。
确定脑瘫患儿睡眠障碍的患病率是本系统评价和荟萃分析的主要目的。
使用预先指定的纳入标准，在MEDLINE、Embase、Scopus、ScienceDirect和Web of Science上对所有相关文章进行电子检索。使用R 4.3.2版本，通过随机效应模型计算患有睡眠问题的脑瘫患儿的合并比例。
更新后的系统评价和荟萃分析纳入了42项研究。儿童睡眠障碍量表（SDSC）显示，26%（95%CI：17%-37%）的脑瘫患儿得分异常。子量表异常包括入睡和维持睡眠障碍（28%）、睡眠呼吸障碍（17%）、过度嗜睡（12%）、睡眠多汗症（10%）和睡眠-觉醒转换障碍（19%）。儿童睡眠问卷（PSQ）显示，39%（95%CI：6%-80%）的儿童得分异常。敏感性分析证实了这些结果，不过在PSQ结果中发现了一些发表偏倚。
约四分之一的脑瘫患儿存在睡眠问题，这可能会使他们的生活质量下降。为了提高脑瘫患儿的生活质量，定期进行睡眠检查和针对性治疗是必要的。
