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纳洛酮认知与获取:2021 - 2022年加拿大高等教育酒精与药物使用调查结果

Naloxone awareness and acquisition: Findings from the 2021‒2022 Canadian Postsecondary Education Alcohol and Drug Use Survey.

作者信息

Burt Jacqueline, Krzeminska Emilia

机构信息

Office of Drug Research and Surveillance, Health Canada, Ottawa, ON, Canada.

出版信息

Can J Public Health. 2025 Apr 28. doi: 10.17269/s41997-025-01034-4.

Abstract

OBJECTIVES

This cross-sectional study assessed naloxone awareness, acquisition rates, and reasons for acquisition among postsecondary students in Canada aged 17‒25 years.

METHODS

Using data from the 2021‒2022 Canadian Postsecondary Education Alcohol and Drug Use Survey, we conducted descriptive analyses of 31,643 students to characterize naloxone awareness, acquisition, and reasons for acquisition overall and by age, gender, race, international student status, and opioid pain reliever (OPR) use. Using multivariable logistic regression, we assessed the relationship between demographic variables and naloxone awareness and acquisition.

RESULTS

Among postsecondary students in Canada, only 47% had heard of naloxone, and only 5% had acquired it in the past year. Significant predictors of naloxone awareness and acquisition included gender, age, race, international student status, and OPR use. Older students, non-binary students, domestic students, and Indigenous students had higher odds of both naloxone awareness and acquisition. Students who had used OPRs in the past year were less likely to be aware of naloxone (AOR = 0.85, 95% CI: 0.80-0.91). However, among those who were aware, they were more likely to have acquired naloxone (AOR = 1.16, 95% CI: 1.01-1.34) than those who had not used OPRs. Among students who had acquired naloxone in the past year, 97% reported their main reason for obtaining it was for use in emergencies involving other people.

CONCLUSION

Low naloxone awareness and acquisition among postsecondary students in Canada represent an important public health gap. Increasing naloxone awareness and acquisition may play an important role in enhancing safety on campuses and beyond.

摘要

目的

本横断面研究评估了加拿大17至25岁的大专学生对纳洛酮的知晓情况、获取率以及获取原因。

方法

利用2021 - 2022年加拿大高等教育酒精与药物使用调查的数据,我们对31643名学生进行了描述性分析,以总体及按年龄、性别、种族、国际学生身份和阿片类镇痛药(OPR)使用情况来描述纳洛酮的知晓、获取及获取原因。通过多变量逻辑回归,我们评估了人口统计学变量与纳洛酮知晓和获取之间的关系。

结果

在加拿大的大专学生中,只有47%听说过纳洛酮,过去一年中只有5%获取过纳洛酮。纳洛酮知晓和获取的显著预测因素包括性别、年龄、种族、国际学生身份和OPR使用情况。年龄较大的学生、非二元性别学生、本国学生和原住民学生知晓纳洛酮并获取纳洛酮的几率更高。过去一年使用过OPR的学生知晓纳洛酮的可能性较小(调整后比值比[AOR]=0.85,95%置信区间[CI]:0.80 - 0.91)。然而,在知晓纳洛酮的学生中,他们获取纳洛酮的可能性(AOR = 1.16,95% CI:1.01 - 1.34)比未使用过OPR的学生更高。在过去一年获取过纳洛酮的学生中,97%报告获取纳洛酮的主要原因是用于涉及他人的紧急情况。

结论

加拿大大专学生对纳洛酮的知晓率和获取率较低,这是一个重要的公共卫生差距。提高纳洛酮的知晓率和获取率可能在加强校园及其他场所的安全方面发挥重要作用。

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