Schuetz E, Schaefer R M, Heidbreder E, Heidland A
Klin Wochenschr. 1985 Jul 1;63(13):575-7. doi: 10.1007/BF01733007.
The differentiation between glomerular and non-glomerular haematuria by phase-contrast microscopy has proved to be a useful tool in the diagnosis of glomerulonephritis. In an attempt to evaluate the effect of marked diuresis on the altered red cell morphology in patients with biopsy proven glomerulonephritis, urinary sediments were examined following water or furosemide-induced diuresis. In both diuretic states urine flow increased, urine osmolality decreased and the percentage of glomerular erythrocytes was significantly reduced in the urinary sediment. These data demonstrate that the alteration in urinary red cells in glomerulonephritis is mainly caused by tubular forces. The diagnostic significance is reduced during increased diuresis and the evaluation of urinary red cell morphology should not be performed.
通过相差显微镜区分肾小球性血尿和非肾小球性血尿已被证明是诊断肾小球肾炎的一种有用工具。为了评估显著利尿对经活检证实为肾小球肾炎患者红细胞形态改变的影响，在水或速尿诱导利尿后检查尿沉渣。在两种利尿状态下，尿流量增加，尿渗透压降低，尿沉渣中肾小球性红细胞百分比显著降低。这些数据表明，肾小球肾炎患者尿红细胞的改变主要是由肾小管力引起的。在利尿增加期间诊断意义降低，不应进行尿红细胞形态的评估。
