Long-Term Follow-up of Cytomegalovirus Retinitis in an Immunocompetent Patient.

To describe the long-term follow-up of an immunocompetent patient with cytomegalovirus (CMV) retinitis. A single case was analyzed and a literature review performed. A 47-year-old woman presented with a paracentral scotoma in the left eye. Examination showed parafoveal retinitis. An aqueous fluid tap was positive for CMV on polymerase chain reaction; however, there was no recent surgery or local or systemic immunosuppression. A thorough workup, including pan imaging, was unremarkable. The retinitis resolved with oral valganciclovir and adjuvant intravitreal ganciclovir and foscarnet injections. At the 3-year follow-up, the patient's disease was inactive without development of systemic illness. In patients presenting with retinitis, the diagnostic use of aqueous polymerase chain reaction is critical, especially in atypical cases in which the retinitis might be associated with CMV.