Liu Sidi, Liu Yang, Li Ming, Shang Shuangshuang, Cao Yunxiang, Shen Xi, Huang Chuanbing
Department of Rheumatology and Immunology, The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, Anhui, China.
Center for Xin'an Medicine and Modernization of Traditional Chinese Medicine of Institute of Health and Medicine (IHM), The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, Anhui, China.
Front Immunol. 2025 Apr 22;16:1525462. doi: 10.3389/fimmu.2025.1525462. eCollection 2025.
Autoimmune diseases have long been recognized for their intricate nature and elusive mechanisms, presenting significant challenges in both diagnosis and treatment. The advent of artificial intelligence technology has opened up new possibilities for understanding, diagnosing, predicting, and managing autoimmune disorders. This study aims to explore the current state and emerging trends in the field through bibliometric analysis, providing guidance for future research directions.
The study employed the Web of Science Core Collection database for data acquisition and performed bibliometric analysis using CiteSpace, HistCite Pro, and VOSviewer.
Over the past two decades, 1,695 publications emerged in this research field, including 1,409 research articles and 286 reviews. This investigation unveils the global development landscape predominantly led by the United States and China. The research identifies key institutions, such as Brigham & Women's Hospital, influential journals like the Annals of the Rheumatic Diseases, distinguished authors including Katherine P. Liao, and pivotal articles. It visually maps out the research clusters' evolutionary path over time and explores their applications in patient identification, risk factors, prognosis assessment, diagnosis, classification of disease subtypes, monitoring and decision support, and drug discovery.
AI is increasingly recognized for its potential in the field of autoimmune diseases, yet it continues to face numerous challenges, including insufficient model validation and difficulties in data integration and computational power. Significant advancements have been demanded to enhance diagnostic precision, improve treatment methodologies, and establish robust frameworks for data protection, thereby facilitating more effective management of these complex conditions.
自身免疫性疾病长期以来因其复杂的性质和难以捉摸的机制而为人所知,在诊断和治疗方面都带来了重大挑战。人工智能技术的出现为理解、诊断、预测和管理自身免疫性疾病开辟了新的可能性。本研究旨在通过文献计量分析探索该领域的现状和新趋势,为未来的研究方向提供指导。
本研究利用科学网核心合集数据库进行数据采集,并使用CiteSpace、HistCite Pro和VOSviewer进行文献计量分析。
在过去二十年中,该研究领域共出现了1695篇出版物,其中包括1409篇研究论文和286篇综述。本次调查揭示了以美国和中国为主导的全球发展格局。该研究确定了关键机构,如布莱根妇女医院;有影响力的期刊,如《风湿病学年鉴》;杰出作者,包括廖凯瑟琳·P;以及关键文章。它直观地描绘了研究集群随时间的演变路径,并探索了它们在患者识别、风险因素、预后评估、诊断、疾病亚型分类、监测和决策支持以及药物发现中的应用。
人工智能在自身免疫性疾病领域的潜力日益得到认可,但它仍面临众多挑战,包括模型验证不足以及数据整合和计算能力方面的困难。需要取得重大进展以提高诊断精度、改进治疗方法并建立强大的数据保护框架,从而更有效地管理这些复杂病症。