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叙利亚大马士革自发性脑出血患者危险因素的患病率:一项回顾性横断面研究

Prevalence of Risk Factors in Patients With Spontaneous Intracerebral Hemorrhage in Damascus_Syria: A Retrospective Cross-Sectional Study.

作者信息

Ala Rashi Mohamad, Alkhateeb Khaled, Altabbaa Hamza, Alnehlawi Omar, Nakawah Aman, Hamzeh Ghassan

机构信息

Faculty of Medicine Damascus University Damascus Syria.

Internal Medicine Department, Faculty of Medicine Damascus University Damascus Syria.

出版信息

Health Sci Rep. 2025 May 5;8(5):e70781. doi: 10.1002/hsr2.70781. eCollection 2025 May.

DOI:10.1002/hsr2.70781
PMID:40330745
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12051432/
Abstract

OBJECTIVES

This study aims to determine the prevalence of risk factors among patients with spontaneous intracerebral hemorrhage in Syrian society.

METHODS

This study is a retrospective cross-sectional study, patients' data were collected from four hospitals. Cross-tabulation tables and the test were used to show the relationship between gender/age and the prevalence of risk factors, demonstrate statistical significance, and calculate value.

RESULTS

From a total of 194 patients included in the study, there were 123 males, accounting for 63.4% of the patients, while there were 71 females, accounting for 36.6%. The most common risk factor among intracerebral hemorrhage patients was hypertension at 44.8% of the total patients, followed by antithrombotic use at 25.8%, smoking at 19.1%, diabetes at 15.5%, and hematological diseases making up 9.3% of the patients, whereas in age groups under 10 years, various hematological diseases were the most prevalent risk factors at 42.5%, followed by prematurity at 27.5%, and hyaline membrane disease at 15%. The study showed no statistically significant differences in the distribution of risk factors between males and females except for smoking. However, the results revealed a significant difference in the distribution of risk factors according to age for Smoking, hypertension, antithrombotic use, diabetes, arteriovenous malformation, hyaline membrane disease, hematological diseases, and prematurity ( < 0.05).

CONCLUSION

The study showed that hypertension and antithrombotic use are the most important risk factors for intracerebral hemorrhage, so controlling arterial pressure and periodic tests such as platelet count/PT/PTT are gold roles in preventing intracerebral hemorrhage.

摘要

目的

本研究旨在确定叙利亚社会自发性脑出血患者中危险因素的患病率。

方法

本研究为回顾性横断面研究,从四家医院收集患者数据。使用交叉表和检验来显示性别/年龄与危险因素患病率之间的关系,证明统计学意义,并计算值。

结果

在纳入研究的194例患者中,男性123例,占患者总数的63.4%,女性71例,占36.6%。脑出血患者中最常见的危险因素是高血压,占总患者数的44.8%,其次是抗栓药物使用,占25.8%,吸烟占19.1%,糖尿病占15.5%,血液系统疾病占患者的9.3%,而在10岁以下年龄组中,各种血液系统疾病是最普遍的危险因素,占42.5%,其次是早产,占27.5%,透明膜病占15%。研究表明,除吸烟外,男性和女性之间危险因素的分布无统计学显著差异。然而,结果显示,吸烟、高血压、抗栓药物使用、糖尿病、动静脉畸形、透明膜病、血液系统疾病和早产的危险因素分布按年龄有显著差异(<0.05)。

结论

研究表明,高血压和抗栓药物使用是脑出血最重要的危险因素,因此控制动脉血压和定期进行血小板计数/PT/PTT等检查是预防脑出血的关键措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a81e/12051432/06c41b938a12/HSR2-8-e70781-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a81e/12051432/817948eca794/HSR2-8-e70781-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a81e/12051432/fc543ae9c342/HSR2-8-e70781-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a81e/12051432/06c41b938a12/HSR2-8-e70781-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a81e/12051432/817948eca794/HSR2-8-e70781-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a81e/12051432/fc543ae9c342/HSR2-8-e70781-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a81e/12051432/06c41b938a12/HSR2-8-e70781-g003.jpg

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本文引用的文献

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Int J Gen Med. 2024 Jun 25;17:2865-2875. doi: 10.2147/IJGM.S470314. eCollection 2024.
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Risk factors and a prediction model for the prognosis of intracerebral hemorrhage using cerebral microhemorrhage and clinical factors.
利用脑微出血和临床因素预测脑出血预后的危险因素及预测模型
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