法国因缺血性卒中和脑出血住院的患者：时间趋势（2008 - 2019年）、住院结局、年龄和性别差异
Patients Hospitalized for Ischemic Stroke and Intracerebral Hemorrhage in France: Time Trends (2008-2019), In-Hospital Outcomes, Age and Sex Differences.
作者信息
Olié Valérie, Grave Clémence, Tuppin Philippe, Duloquin Gauthier, Béjot Yannick, Gabet Amélie
机构信息
Department of Non-Communicable Diseases, Santé Publique France, 94410 Saint-Maurice, France.
Department of Health Studies and Statistics, Caisse Nationale de l'Assurance Maladie, 75020 Paris, France.
出版信息
J Clin Med. 2022 Mar 17;11(6):1669. doi: 10.3390/jcm11061669.
BACKGROUND
Rates of patients hospitalized for stroke increased among people aged under 65 years in France, as has been found in other countries.
METHODS
To analyze time trends in the rates of patients hospitalized for ischemic stroke (IS) and intracerebral hemorrhage (ICH) in France between 2008 and 2019 and determine related short-term outcomes mainly, we selected all patients hospitalized for stroke using the French national hospital database.
RESULTS
The average annual percentage change in the rates of patients hospitalized for IS increased significantly in men and women aged 50-64 years (+2.0%) and in men aged 18-34 years (+1.5%) and 35-44 years (+2.2%). A decrease in the average annual percentage change was observed for IS among people aged over 75 years and among those over 50 years for ICH. After adjustment on confounding factors, women were less likely to die in hospital. Case fatality rates decreased overtime in all age groups for both sexes, with a more pronounced decrease for IS than ICH.
CONCLUSIONS
The increasing trend of IS among adults under 65 years is ongoing, highlighting the urgent need for stroke prevention programs in that age. For the first time, we recorded a decrease in the rates of patients hospitalized for ICH among the population over 50 years.
背景
正如在其他国家所发现的那样，法国65岁以下人群中因中风住院的患者比例有所上升。
方法
为了分析2008年至2019年法国缺血性中风（IS）和脑出血（ICH）患者住院率的时间趋势，并主要确定相关的短期结局，我们使用法国国家医院数据库选择了所有因中风住院的患者。
结果
50 - 64岁男性和女性以及18 - 34岁男性（+1.5%）和35 - 44岁男性（+2.2%）中，因IS住院患者率的年均百分比变化显著增加。75岁以上人群以及50岁以上人群中ICH患者的IS年均百分比变化有所下降。在对混杂因素进行调整后，女性在医院死亡的可能性较小。所有年龄组中男女的病死率均随时间下降，IS的下降比ICH更为明显。
结论
65岁以下成年人中IS的上升趋势仍在持续，凸显了该年龄段中风预防项目的迫切需求。我们首次记录到50岁以上人群中ICH患者住院率的下降。
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