Wu Zhuo, Piao Xuezhe, Kang Dongxu, Jin Lan, Xu Qiang, Jin Dehao, Piao Longzhen
Department of Oncology, Yanbian University Hospital, Yanji, Jilin, China.
Department of Intervention, Yanbian University Hospital, Yanji, Jilin, China.
Front Oncol. 2025 Apr 22;15:1529976. doi: 10.3389/fonc.2025.1529976. eCollection 2025.
We report the case of an older female patient with squamous cell carcinoma of the skin, cTXN1M0, who initially presented with a mass of approximately 4.5 cm in diameter in the left temporal region, which had a tendency to break and bleed. Given the patient's poor general status and ECOG score of grade 2, it was considered that she could not tolerate systemic chemotherapy. Therefore, we applied drug-eluting beads transarterial chemoembolization combined with immune checkpoint inhibitors to treat this patient and unexpectedly found that this regimen resulted in complete classified remission and in partial pathological response without significant adverse events.
我们报告了一例老年女性皮肤鳞状细胞癌患者，cTXN1M0，最初表现为左颞部一个直径约4.5厘米的肿块，有破溃出血倾向。鉴于患者一般状况较差且东部肿瘤协作组（ECOG）评分为2级，认为她无法耐受全身化疗。因此，我们应用载药微球经动脉化疗栓塞联合免疫检查点抑制剂治疗该患者，意外发现该方案导致完全分类缓解和部分病理缓解，且无明显不良事件。
