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Association between body mass index and diabetes mellitus control classification among patients with type 2 diabetes mellitus: Evidence from the National Diabetes Registry of Muar District Health Office, Malaysia, from January 2021 to July 2023.

作者信息

Mohamad Salleh Muhammad Muzzammil, Isa Mohamad Rodi, Md Yasin Mazapuspavina, Mohd Azahar Nazar, Mohd Lutpi Mohd Ridzuan

机构信息

MBBCh, MPH, Department of Public Health, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, Malaysia.

MBBS, DAP&E, MPH, DrPH, Department of Public Health, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, Malaysia. Email:

出版信息

Malays Fam Physician. 2025 Apr 12;20:23. doi: 10.51866/oa.794. eCollection 2025.


DOI:10.51866/oa.794
PMID:40330983
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12051975/
Abstract

INTRODUCTION: Type 2 diabetes mellitus (T2DM) is one of the most prevalent non-communicable diseases globally. This study aimed to determine the association between body mass index (BMI) and diabetes mellitus (DM) control among patients with T2DM. METHODS: A retrospective study was conducted from October 2023 to June 2024 using secondary data from the National Diabetes Registry (NDR) of Muar District Health Office, Johor. Patients with T2DM registered in the NDR and audited from 2021 to July 2023 were included. The association between BMI and DM control was analysed using hierarchical multinomial logistic regression. RESULTS: A total of 1955 patients were included in the study. The prevalence of good, intermediate and poor BMI control was 38.8% (95% Confident Interval (CI)=36.7, 41.0), 22.2% (95% CI=20.3, 24.0) and 39.0% (95% CI=36.7, 41.2), respectively. Most patients were older Malay women. There was an association between BMI and DM control unadjusted (P<0.001) and adjusted for several confounding factors using seven models (P=0.003-0.034). The R value also improved from 0.008 to 0.293. Conclusion: Among patients with T2DM, a higher BMI, the creatinine level and medications such as glucose-lowering drugs, ticlopidine, acetylsalicylic acid and statins are associated with DM control. However, as the study design does not allow for the assessment of causality or progression over time, the findings should be interpreted as descriptive associations rather than as evidence of cause-and-effect relationships. Focus on medication compliance, healthcare providers' role during medication consultation and stakeholders' role in maintaining drug supplementation is needed.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa5b/12051975/e0770cdb18ae/MFP-20-23-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa5b/12051975/e0770cdb18ae/MFP-20-23-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa5b/12051975/e0770cdb18ae/MFP-20-23-g1.jpg

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本文引用的文献

[1]
Sex Differences in Glucose Homeostasis.

Handb Exp Pharmacol. 2023

[2]
Effects of statin therapy on glycemic control and insulin resistance: A systematic review and meta-analysis.

Eur J Pharmacol. 2023-5-15

[3]
Glycemic control and its influencing factors in type 2 diabetes patients in Anhui, China.

Front Public Health. 2022

[4]
Impact of Older Age Adiposity on Incident Diabetes: A Community-Based Cohort Study in China.

Diabetes Metab J. 2022-9

[5]
Prevalence of type-2 diabetes and prediabetes in Malaysia: A systematic review and meta-analysis.

PLoS One. 2022

[6]
Diabetes severity measured by treatment control status and number of anti-diabetic drugs affects presenteeism among workers with type 2 diabetes.

BMC Public Health. 2021-10-16

[7]
Determinants of glycaemic control among type 2 diabetes mellitus patients in Northern State of Kedah, Malaysia: a cross-sectional analysis of 5 years national diabetes registry 2014-2018.

Pan Afr Med J. 2021

[8]
Anti-diabetic drugs and weight loss in patients with type 2 diabetes.

Pharmacol Res. 2021-9

[9]
Lipid Profile in Indian Patients With Type 2 Diabetes: The Scope for Atherosclerotic Cardiovascular Disease Risk Reduction.

Diabetes Spectr. 2020-11

[10]
Adiposity contributes to poor glycemic control in people with diabetes mellitus, a randomized case study, in South Kashmir, India.

J Family Med Prim Care. 2020-9-30

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