Mohamad Salleh Muhammad Muzzammil, Isa Mohamad Rodi, Md Yasin Mazapuspavina, Mohd Azahar Nazar, Mohd Lutpi Mohd Ridzuan
MBBCh, MPH, Department of Public Health, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, Malaysia.
MBBS, DAP&E, MPH, DrPH, Department of Public Health, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, Malaysia. Email:
Malays Fam Physician. 2025 Apr 12;20:23. doi: 10.51866/oa.794. eCollection 2025.
Type 2 diabetes mellitus (T2DM) is one of the most prevalent non-communicable diseases globally. This study aimed to determine the association between body mass index (BMI) and diabetes mellitus (DM) control among patients with T2DM.
A retrospective study was conducted from October 2023 to June 2024 using secondary data from the National Diabetes Registry (NDR) of Muar District Health Office, Johor. Patients with T2DM registered in the NDR and audited from 2021 to July 2023 were included. The association between BMI and DM control was analysed using hierarchical multinomial logistic regression.
A total of 1955 patients were included in the study. The prevalence of good, intermediate and poor BMI control was 38.8% (95% Confident Interval (CI)=36.7, 41.0), 22.2% (95% CI=20.3, 24.0) and 39.0% (95% CI=36.7, 41.2), respectively. Most patients were older Malay women. There was an association between BMI and DM control unadjusted (P<0.001) and adjusted for several confounding factors using seven models (P=0.003-0.034). The R value also improved from 0.008 to 0.293. Conclusion: Among patients with T2DM, a higher BMI, the creatinine level and medications such as glucose-lowering drugs, ticlopidine, acetylsalicylic acid and statins are associated with DM control. However, as the study design does not allow for the assessment of causality or progression over time, the findings should be interpreted as descriptive associations rather than as evidence of cause-and-effect relationships. Focus on medication compliance, healthcare providers' role during medication consultation and stakeholders' role in maintaining drug supplementation is needed.
2型糖尿病(T2DM)是全球最常见的非传染性疾病之一。本研究旨在确定2型糖尿病患者体重指数(BMI)与糖尿病(DM)控制之间的关联。
2023年10月至2024年6月进行了一项回顾性研究,使用柔佛州麻坡地区卫生局国家糖尿病登记处(NDR)的二手数据。纳入2021年至2023年7月在NDR登记并接受审核的T2DM患者。使用分层多项逻辑回归分析BMI与DM控制之间的关联。
本研究共纳入1955例患者。BMI控制良好、中等和较差的患病率分别为38.8%(95%置信区间(CI)=36.7, 41.0)、22.2%(95% CI=20.3, 24.0)和39.0%(95% CI=36.7, 41.2)。大多数患者为老年马来女性。BMI与DM控制之间在未调整时存在关联(P<0.001),并使用七个模型对多个混杂因素进行调整后仍存在关联(P=0.003 - 0.034)。R值也从0.008提高到0.293。结论:在T2DM患者中,较高的BMI、肌酐水平以及降糖药物、噻氯匹定、乙酰水杨酸和他汀类药物等药物与DM控制相关。然而,由于研究设计不允许评估因果关系或随时间的进展,这些发现应解释为描述性关联,而非因果关系的证据。需要关注药物依从性、医疗保健提供者在药物咨询期间的作用以及利益相关者在维持药物补充方面的作用。