马来西亚吉打州北部 2 型糖尿病患者血糖控制的决定因素：2014-2018 年国家糖尿病登记 5 年的横断面分析。

Determinants of glycaemic control among type 2 diabetes mellitus patients in Northern State of Kedah, Malaysia: a cross-sectional analysis of 5 years national diabetes registry 2014-2018.

机构信息

Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latiff, Bandar Tun Razak, Kuala Lumpur, Malaysia.

Department of Surgery, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia.

出版信息

Pan Afr Med J. 2021 Jul 21;39:206. doi: 10.11604/pamj.2021.39.206.30410. eCollection 2021.

DOI:10.11604/pamj.2021.39.206.30410

PMID:34603587

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8464198/

Abstract

INTRODUCTION

type 2 diabetes mellitus has become a global public health crisis. The increment in the cases has contributed significantly to the parallel increase in the prevalence of overweight and obesity. This paper aimed to analyse the relationship between lipid profile, waist circumference and body mass index (BMI) with the glycaemic control of the diabetes patients in Kedah.

METHODS

a cross-sectional study was conducted, using the Kedah audit samples data extracted from the National Diabetes Registry (NDR) from the year 2014 to 2018. A total of 25,062 registered type 2 diabetes mellitus patients were selected using the inclusion and exclusion criteria from the registry. Only patients with complete data on their HbA1C, lipid profile, waist circumference and BMI were analysed using SPSS version 21.

RESULTS

the means for the age, BMI and waist circumference of the samples were 61.5 (±10.85) years, 27.3 (±5.05) kg/m and 89.46 (±13.58) cm, respectively. Poor glycaemic control (HbA1c>6.5%) was observed in 72.7% of the patients, with females having poorer glycaemic control. The BMI and waist circumference were found to be significantly associated with glycaemic control (P<0.001). The total cholesterol, triglycerides and low-density lipoproteins values showed positive correlation with glycaemic control (r = 0.178, 0.157, 0.145, p<0.001), while high-density lipoproteins values are negatively correlated (r = -0.019, p<0.001).

CONCLUSION

implementing lifestyle changes such as physical activity and dietary modifications are important in the management of BMI, waist circumference and body lipids, which in turn results in improved glycaemic control.

摘要

简介

2 型糖尿病已成为全球公共健康危机。病例的增加导致超重和肥胖患病率的平行增加。本文旨在分析吉打州糖尿病患者的血脂谱、腰围和体重指数（BMI）与血糖控制之间的关系。

方法

采用横断面研究，使用 2014 年至 2018 年从国家糖尿病登记处（NDR）提取的吉打审计样本数据。从登记处使用纳入和排除标准选择了 25062 名登记的 2 型糖尿病患者。仅对 HbA1C、血脂谱、腰围和 BMI 具有完整数据的患者使用 SPSS 版本 21 进行分析。

结果

样本的平均年龄、BMI 和腰围分别为 61.5（±10.85）岁、27.3（±5.05）kg/m 和 89.46（±13.58）cm。观察到 72.7%的患者血糖控制不佳（HbA1c>6.5%），女性血糖控制较差。BMI 和腰围与血糖控制显著相关（P<0.001）。总胆固醇、甘油三酯和低密度脂蛋白值与血糖控制呈正相关（r = 0.178、0.157、0.145，p<0.001），而高密度脂蛋白值呈负相关（r = -0.019，p<0.001）。