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Regenerative Potential Nanomedicine of Adipocyte Stem Cell-Derived Exosomes in Senescent Skin Tissue [Response to Letter].

作者信息

Li An-Na, Sun Jing-Hua, Saidin Syafiqah, Cheah Jee Syuen, Kuo Chia-Hung, Li Ling, Li Jia-Shen, Bai Ru-Yu, Diao Yong, Wang Hui-Min David

机构信息

School of Medicine, Huaqiao University, Quanzhou, Fujian, 362021, People's Republic of China.

Hebei Key Laboratory of Basic Medicine for Diabetes, Shijiazhuang Second Hospital, Shijiazhuang, Hebei, 050000, People's Republic of China.

出版信息

Int J Nanomedicine. 2025 May 1;20:5611-5612. doi: 10.2147/IJN.S525193. eCollection 2025.

DOI:10.2147/IJN.S525193
PMID:40331230
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12052000/
Abstract
摘要

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本文引用的文献

1
A phase 1, open-label study to determine safety and tolerability of the topical application of mesenchymal stem/stromal cell (MSC) exosome ointment to treat psoriasis in healthy volunteers.一项1期开放标签研究，旨在确定向健康志愿者局部应用间充质干/基质细胞（MSC）外泌体软膏治疗银屑病的安全性和耐受性。
Cytotherapy. 2025 May;27(5):633-641. doi: 10.1016/j.jcyt.2025.01.007. Epub 2025 Jan 23.
2
Clinical-grade extracellular vesicles derived from umbilical cord mesenchymal stromal cells: preclinical development and first-in-human intra-articular validation as therapeutics for knee osteoarthritis.源自脐带间充质基质细胞的临床级细胞外囊泡：作为膝骨关节炎治疗药物的临床前开发及首次人体关节内验证
J Nanobiotechnology. 2025 Jan 13;23(1):13. doi: 10.1186/s12951-024-03088-x.
3
Evaluating the safety and efficacy of mesenchymal stem cell-derived exosomes for treatment of refractory perianal fistula in IBD patients: clinical trial phase I.评估间充质干细胞衍生外泌体治疗IBD患者难治性肛瘘的安全性和有效性：I期临床试验
Gastroenterol Rep (Oxf). 2022 Dec 9;10:goac075. doi: 10.1093/gastro/goac075. eCollection 2022.