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人乳头瘤病毒疫苗:如果该疫苗很重要且可获取,为何不使用呢?

Human papillomavirus vaccination: if the vaccine is important and available, why not use it?

作者信息

Freire Georgiana Sousa, Amaral Carolina Lavacchini Ramunno, Romano Juliana Jorge, Bussamra Aulicino Camila, Sette Cláudia Vaz de Melo, Bonometto Juliana Vieira Biason, Maselli-Schoueri Jean Henri, Sousa Luiz Vinicius de Alcantara, Giglio Auro Del, Cubero Daniel de Iracema Gomes

机构信息

Centro Universitário Faculdade de Medicina do ABC - Santo André (SP), Brazil.

Centro Universitário Faculdade de Medicina do ABC, Department of Oncology - Santo André (SP), Brazil.

出版信息

Rev Assoc Med Bras (1992). 2025 May 2;71(3):e20240865. doi: 10.1590/1806-9282.20240865. eCollection 2025.

Abstract

BACKGROUND

Human papillomavirus (HPV) is the most common virus of the reproductive tract, is linked to cervical cancer, and can be prevented by vaccination, which is most effective if the vaccine is administered before sexual activity begins.

METHODS

This descriptive, cross-sectional, and qualitative study was based on a survey containing 15 questions delivered to schools in three cities in the ABC region. Two schools from high-income neighborhoods and two from low-income neighborhoods were selected in each city based on real estate values. Data were expressed in absolute numbers and percentages and interpreted by descriptive analysis. The statistical tests of association were performed.

RESULTS

Twelve schools were invited and nine agreed to participate. Of the 4,503 questionnaires delivered, 1,921 were completed by parents and guardians. The vaccination rate was 56.05% in private schools and 66.58% in public schools. Private vs. public school was not an independent factor for vaccination, but residing in a low-income neighborhood and city was a determinant factor. Approximately 40% of the parents/guardians reported not having their children vaccinated, primarily due to concerns about adverse effects.

CONCLUSION

Despite being freely available and proven effective, the human papillomavirus vaccine remains underutilized. The reasons exposed in this paper may be useful in strategies to enhance vaccination coverage.

TRIAL REGISTRATION

This study was approved by the research ethics committee under the number 2.143.196.

摘要

背景

人乳头瘤病毒(HPV)是生殖道最常见的病毒,与宫颈癌有关,可通过接种疫苗预防,若在开始性行为前接种疫苗则最为有效。

方法

本描述性、横断面和定性研究基于一项调查,该调查包含15个问题,发放给ABC地区三个城市的学校。根据房地产价值,在每个城市选取两所高收入社区学校和两所低收入社区学校。数据以绝对数和百分比表示,并通过描述性分析进行解读。进行了关联性统计检验。

结果

共邀请了12所学校,9所同意参与。在发放的4503份问卷中,1921份由家长和监护人完成。私立学校的疫苗接种率为56.05%,公立学校为66.58%。私立学校与公立学校并非疫苗接种的独立影响因素,但居住在低收入社区和城市是一个决定性因素。约40%的家长/监护人报告未给孩子接种疫苗,主要原因是担心不良反应。

结论

尽管人乳头瘤病毒疫苗免费且已证明有效,但仍未得到充分利用。本文揭示的原因可能有助于提高疫苗接种覆盖率的策略制定。

试验注册

本研究经研究伦理委员会批准,批准号为2.143.196。

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