18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描最大标准化摄取值(SUVMax)在决定对实性孤立性肺结节进行计算机断层扫描引导下肺活检中的作用。

The role of 18F-fluorodeoxyglucose positron emission tomography/computed tomography SUVMax in deciding on a computed tomography-guided lung biopsy in solid solitary pulmonary nodules.

作者信息

Ulusoy Bekir Sıtkı Said, Binboga Ali Burak, Onay Mehmet, Altay Cetin Murat, Kara Ahmet Burak

机构信息

University of Health Sciences, Gaziantep City Hospital, Department of Radiology - Gaziantep, Turkey.

出版信息

Rev Assoc Med Bras (1992). 2025 May 2;71(3):e20241741. doi: 10.1590/1806-9282.20241741. eCollection 2025.

Abstract

OBJECTIVE

The aim of this study was to calculate a useful cut-off point of the 18F-fluorodeoxyglucose positron emission tomography/computed tomography SUVMax value to decide on a computed tomography-guided percutaneous transthoracic needle biopsy for solitary pulmonary nodules of sizes between 11 and 20 mm.

METHODS

Between January 2015 and April 2020, patients with solitary pulmonary nodules who underwent computed tomography-guided percutaneous transthoracic needle biopsy were retrospectively reviewed, and those with solitary pulmonary nodules of 11-20 mm in diameter, who had undergone an 18F-fluorodeoxyglucose positron emission tomography/computed tomography examination before computed tomography-guided percutaneous transthoracic needle biopsy, were included in the study. A total of 76 patients who met the inclusion criteria were evaluated.

RESULTS

There was no distinguishing finding on the computed tomography examination (p>0.05). The SUVMax values of the malignant solid solitary pulmonary nodules were higher than the benign solitary pulmonary nodules (p<0.05).

CONCLUSION

The benign and malignant solid solitary pulmonary nodules between 11 and 20 mm have similar computed tomography features. 18F-fluorodeoxyglucose positron emission tomography/computed tomography is a useful imaging technique for distinguishing benign and malignant solitary pulmonary nodules. Notably, 4.85 SUVMax value can be used to decide on a computed tomography-guided percutaneous transthoracic needle biopsy procedure in solid solitary pulmonary nodules between 11 and 20 mm with excellent sensitivity and moderate specificity rates.

摘要

目的

本研究旨在计算18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描最大标准摄取值(SUVMax)的有效截断点,以决定对直径在11至20毫米之间的孤立性肺结节进行计算机断层扫描引导下经皮经胸针吸活检。

方法

回顾性分析2015年1月至2020年4月间接受计算机断层扫描引导下经皮经胸针吸活检的孤立性肺结节患者,纳入在计算机断层扫描引导下经皮经胸针吸活检前接受过18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描检查、直径为11 - 20毫米的孤立性肺结节患者。共评估了76例符合纳入标准的患者。

结果

计算机断层扫描检查无鉴别性发现(p>0.05)。恶性实性孤立性肺结节的SUVMax值高于良性孤立性肺结节(p<0.05)。

结论

11至20毫米之间的良性和恶性实性孤立性肺结节具有相似的计算机断层扫描特征。18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描是鉴别良性和恶性孤立性肺结节的有用成像技术。值得注意的是,4.85的SUVMax值可用于决定对11至20毫米的实性孤立性肺结节进行计算机断层扫描引导下经皮经胸针吸活检,其敏感性高,特异性中等。

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