López-Cabrera Yessica
Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Unidad de Trasplante Renal. Ciudad de México, México.
Rev Med Inst Mex Seguro Soc. 2025 May 2;63(3):e6268. doi: 10.5281/zenodo.15178491.
Kidney transplantation is the replacement therapy of choice in patients with end-stage chronic kidney disease; however, complications such as delayed graft function increase the risk of rejection and reduce survival. It has been made a search of biomarkers as accessible, and reproducible low-cost tools that allow to predict risk. Among them, it has been evaluated the neutrophil-lymphocyte index, an inflammatory biomarker associated with ischemia-reperfusion lesion present in these patients. It was made a review to evaluate its predictive usefulness in post-transplant evaluation and follow-up.
肾移植是终末期慢性肾病患者的首选替代治疗方法;然而,诸如移植肾功能延迟等并发症会增加排斥反应的风险并降低生存率。人们一直在寻找可作为易于获取、可重复且低成本的工具来预测风险的生物标志物。其中,已对中性粒细胞与淋巴细胞比值进行了评估,它是一种与这些患者中存在的缺血再灌注损伤相关的炎症生物标志物。本研究进行了一项综述,以评估其在移植后评估和随访中的预测效用。