Sanz Olea Enrique, Hernández Jesus León, Artíñano Begoña, Briz Verónica, Karakitsios Spyros, Sarigiannis Dimosthenis, García Dos Santos Saul, Nuñez-Corcuera Beatriz, Ramis Rebeca
Hospital Universitario La Paz, Madrid, Spain.
Hospital General Universitario de Ciudad Real, Ciudad Real, Spain.
PLoS One. 2025 May 7;20(5):e0322874. doi: 10.1371/journal.pone.0322874. eCollection 2025.
Accepting the fact of a growing urban population and associated health risks, such as increased exposure to pollutants, and considering the high prevalence of chronic diseases, this study aims to investigate the relationship between exposure to environmental noise and depression. The primary objective is to determine the potential mediating role of chronic diseases in this relationship. This study is part of the European H2020 URBANOME project, designed to explore the relationship between the environment and health in urban settings. The main goal of the project is to promote urban health, well-being, and liveability by systematically integrating health concerns into urban policies and civic activities.
We obtained the data for this study from the Madrid City Health Survey, conducted through computer-assisted telephone interviews. Outcome variables assessed through self-reports included depression, exposure to environmental noise, and the presence of chronic diseases. We used a counterfactual mediation framework, implemented by the R package multimediate, to evaluate the potential mediating role of chronic diseases in the relationship between exposure to environmental noise and depression.
The study included 8,445 interviews, with a higher percentage of women (54.67%) than men. 23.29% were over 65, and 17.17% under 30. Notably, 7.82% reported depression, 39.53% had chronic diseases, and 35.43% acknowledged noise exposure. In our regression models, those exposed to environmental noise were 1.24 times more likely to have a chronic disease, and individuals with a chronic disease were 2.93 times more likely to suffer from depression. Participants exposed to environmental noise had 1.03 times more depression, being the 13% of the noise health effect mediated by the presence of chronic illness.
Our findings suggest a link between environmental noise exposure and depression, potentially mediated by chronic diseases. This points out the need for public health interventions to reduce urban noise exposure and improve mental health. Furthermore, prospective studies are needed for confirmation, incorporating noise level measurements and temporal data on the onset of chronic diseases and depression.
鉴于城市人口不断增长以及随之而来的健康风险,如接触污染物增加,同时考虑到慢性病的高患病率,本研究旨在调查环境噪声暴露与抑郁症之间的关系。主要目标是确定慢性病在这种关系中可能起到的中介作用。本研究是欧洲“地平线2020”城市健康项目(URBANOME)的一部分,该项目旨在探索城市环境与健康之间的关系。该项目的主要目标是通过将健康问题系统地纳入城市政策和公民活动来促进城市健康、福祉和宜居性。
我们从马德里市健康调查中获取本研究的数据,该调查通过计算机辅助电话访谈进行。通过自我报告评估的结果变量包括抑郁症、环境噪声暴露以及慢性病的存在情况。我们使用由R包multimediate实现的反事实中介框架,来评估慢性病在环境噪声暴露与抑郁症关系中可能起到的中介作用。
该研究包括8445次访谈,女性比例(54.67%)高于男性。23.29%的受访者年龄超过65岁,17.17%的受访者年龄在30岁以下。值得注意的是,7.82%的受访者报告有抑郁症,39.53%的受访者患有慢性病,35.4%的受访者承认有噪声暴露。在我们的回归模型中,接触环境噪声的人患慢性病的可能性高出1.24倍,患有慢性病的人患抑郁症的可能性高出2.93倍。接触环境噪声的参与者患抑郁症的可能性高出1.03倍,慢性病的存在介导了噪声对健康影响的13%。
我们的研究结果表明,环境噪声暴露与抑郁症之间存在联系,慢性病可能起到中介作用。这表明需要采取公共卫生干预措施来减少城市噪声暴露并改善心理健康。此外,需要进行前瞻性研究以进行确认,纳入噪声水平测量以及慢性病和抑郁症发病的时间数据。