Kubura Dessalegn Tekalign, Mekonnen Gebrehiwot Berie, Nigisi Habtamu Damalash, Shibiru Tesfaye, Legesse Bruck Tesfaye
Department of Pediatrics and Child Health Nursing, Nekemte Comprehensive Specialized Hospital, Ethiopia.
Department of Pediatrics and Child Health Nursing, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.
J Pediatr Nurs. 2025 Jul-Aug;83:160-167. doi: 10.1016/j.pedn.2025.05.001. Epub 2025 May 6.
Child mortality related to intensive care unit admission is a contributor to child death, which is preventable to some extent if identified early. This study aimed to determine the incidence and predictors of mortality among children admitted to intensive care units in tertiary hospitals in West Ethiopia.
A retrospective follow-up study involving 578 admitted children from June 1, 2018, to May 30, 2023, was conducted in western Ethiopia. Data was entered into Epi-Data and then exported to STATA version 14 for analysis. The Cox proportional hazard assumption was checked. The best-fitted model for the data analysis was chosen based on the Akaike information criteria. The hazard ratio was used to measure the strength of the association at p-value <0.05 with 95 % CI.
578 charts were reviewed, and two hundred (34.6 %) children died. The incidence of mortality was 42.5 deaths per 1000-day observations. The median survival time was 15 days (95 % CI: 13 to 18). The need for Inotropes (AHR 2.1; 95 % CI: 1.34-3.09], complications in ICU (AHR 3.5, 95 % CI: 2.2-5.78], GCS < 8 (AHR 1.72, 95 % CI: 1.22-2.46], acute kidney injury (AHR 2.0, 95 % CI: 1.12-3.59] and Age < 5 years (AHR 1.91, 95 % CI: 1.26-2.896] were independent predictors of mortality.
The incidence of mortality was 42.5 deaths per 1000 pediatric day observations. Acute kidney injury, the need for inotropes, age < 5 years, low Glasgow coma scale, and complications developed in the intensive care unit were independent predictors of death.
与重症监护病房收治相关的儿童死亡率是导致儿童死亡的一个因素，如果能早期识别，在一定程度上是可以预防的。本研究旨在确定埃塞俄比亚西部三级医院重症监护病房收治儿童的死亡率及预测因素。
在埃塞俄比亚西部进行了一项回顾性随访研究，纳入了2018年6月1日至2023年5月30日期间收治的578名儿童。数据录入Epi-Data，然后导出到STATA 14版本进行分析。检查了Cox比例风险假设。根据赤池信息准则选择数据分析的最佳拟合模型。风险比用于衡量p值<0.05、95%置信区间时关联的强度。
共审查了578份病历，200名（34.6%）儿童死亡。死亡率为每1000天观察期42.5例死亡。中位生存时间为15天（95%置信区间：13至18天）。使用血管活性药物（风险比2.1；95%置信区间：1.34 - 3.09）、重症监护病房并发症（风险比3.5，95%置信区间：2.2 - 5.78）、格拉斯哥昏迷量表评分<8（风险比1.72，95%置信区间：
