Seino Satoshi, Hata Toshiki, Mori Hiroki, Shinkai Shoji, Fujiwara Yoshinori, Kobayashi Erika
Research Team for Social Participation and Healthy Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology.
Institute of Well-Being, Yamagata University.
J Epidemiol. 2025 May 3. doi: 10.2188/jea.JE20240464.
New long-term care insurance (LTCI) certifications and mortality are key outcomes in cohort studies involving older adults; however, the coronavirus disease 2019 (COVID-19)'s comprehensive impacts on these outcomes remain underexplored. We examined the pandemic's impact on new LTCI applications and all-cause mortality in a metropolitan cohort.
In 2016, 15,500 individuals aged 65-84 years were randomly selected through stratified sampling from Ota City, Tokyo. LTCI and death records were tracked through December 2023; the monthly LTCI applications and all-cause deaths per 10,000 people were calculated. The COVID-19 pandemic period was defined as beginning in March 2020, after the World Health Organization Director-General characterized the situation as a pandemic on March 11, 2020. Interrupted time-series segmented regression analysis was used to compare trends pre- (January 2018-February 2020) and post-pandemic onset (March 2020-December 2023).
From January 2018 to December 2023, 4083 new LTCI applications and 2457 deaths were recorded. New monthly LTCI applications showed a modest upward trend pre-pandemic (0.4 per 10,000 people, 95% confidence interval [CI]: 0.1-0.8), declined sharply at the pandemic's onset (-9.6 per 10,000 people, 95% CI: -16.0 to -3.2), and subsequently increased at a higher rate than pre-pandemic levels (0.8 per 10,000 people, 95% CI: 0.6-1.0). Monthly all-cause deaths remained stable before and immediately after the pandemic's onset but rose slightly in the post-pandemic period (0.3 per 10,000 people per month, 95% CI: 0.2-0.5).
The COVID-19 pandemic influenced both new LTCI applications and all-cause mortality in this study. These impacts should be carefully considered in cohort studies examining these outcomes.
新的长期护理保险(LTCI)认证和死亡率是涉及老年人的队列研究中的关键结果;然而,2019年冠状病毒病(COVID-19)对这些结果的全面影响仍未得到充分探索。我们研究了疫情对一个大都市队列中新的LTCI申请和全因死亡率的影响。
2016年,通过分层抽样从东京大田市随机选取了15500名65 - 84岁的个体。追踪LTCI和死亡记录至2023年12月;计算每月每10000人中的LTCI申请数和全因死亡数。COVID-19大流行期定义为从2020年3月开始,即世界卫生组织总干事于2020年3月11日将该情况定性为大流行之后。采用中断时间序列分段回归分析来比较大流行前(2018年1月 - 2020年2月)和大流行开始后(2020年3月 - 2023年12月)的趋势。
从2018年1月到2023年12月,记录了4083份新的LTCI申请和2457例死亡。每月新的LTCI申请在大流行前呈适度上升趋势(每10000人中有0.4份,95%置信区间[CI]:0.1 - 0.8),在大流行开始时急剧下降(每10000人中有 - 9.6份,95% CI: - 16.0至 - 3.2),随后以高于大流行前水平的速率增加(每10000人中有0.8份,95% CI:0.6 - 1.0)。每月全因死亡数在大流行开始前后保持稳定,但在大流行后时期略有上升(每月每10000人中有0.3例,95% CI:0.2 - 0.5)。
在本研究中,COVID-19大流行影响了新的LTCI申请和全因死亡率。在研究这些结果的队列研究中应仔细考虑这些影响。