• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

COVID-19大流行对日本大都市队列中老年人新长期护理保险申请和全因死亡率的影响:一项中断时间序列分析

Impact of the COVID-19 Pandemic on New Long-term Care Insurance Applications and All-Cause Mortality in Older Adults in a Japanese Metropolitan Cohort: An Interrupted Time-Series Analysis.

作者信息

Seino Satoshi, Hata Toshiki, Mori Hiroki, Shinkai Shoji, Fujiwara Yoshinori, Kobayashi Erika

机构信息

Research Team for Social Participation and Healthy Aging, Tokyo Metropolitan Institute for Geriatrics and Gerontology.

Institute of Well-Being, Yamagata University.

出版信息

J Epidemiol. 2025 May 3. doi: 10.2188/jea.JE20240464.

DOI:10.2188/jea.JE20240464
PMID:40335294
Abstract

PURPOSE

New long-term care insurance (LTCI) certifications and mortality are key outcomes in cohort studies involving older adults; however, the coronavirus disease 2019 (COVID-19)'s comprehensive impacts on these outcomes remain underexplored. We examined the pandemic's impact on new LTCI applications and all-cause mortality in a metropolitan cohort.

METHODS

In 2016, 15,500 individuals aged 65-84 years were randomly selected through stratified sampling from Ota City, Tokyo. LTCI and death records were tracked through December 2023; the monthly LTCI applications and all-cause deaths per 10,000 people were calculated. The COVID-19 pandemic period was defined as beginning in March 2020, after the World Health Organization Director-General characterized the situation as a pandemic on March 11, 2020. Interrupted time-series segmented regression analysis was used to compare trends pre- (January 2018-February 2020) and post-pandemic onset (March 2020-December 2023).

RESULTS

From January 2018 to December 2023, 4083 new LTCI applications and 2457 deaths were recorded. New monthly LTCI applications showed a modest upward trend pre-pandemic (0.4 per 10,000 people, 95% confidence interval [CI]: 0.1-0.8), declined sharply at the pandemic's onset (-9.6 per 10,000 people, 95% CI: -16.0 to -3.2), and subsequently increased at a higher rate than pre-pandemic levels (0.8 per 10,000 people, 95% CI: 0.6-1.0). Monthly all-cause deaths remained stable before and immediately after the pandemic's onset but rose slightly in the post-pandemic period (0.3 per 10,000 people per month, 95% CI: 0.2-0.5).

CONCLUSIONS

The COVID-19 pandemic influenced both new LTCI applications and all-cause mortality in this study. These impacts should be carefully considered in cohort studies examining these outcomes.

摘要

目的

新的长期护理保险(LTCI)认证和死亡率是涉及老年人的队列研究中的关键结果;然而,2019年冠状病毒病(COVID-19)对这些结果的全面影响仍未得到充分探索。我们研究了疫情对一个大都市队列中新的LTCI申请和全因死亡率的影响。

方法

2016年,通过分层抽样从东京大田市随机选取了15500名65 - 84岁的个体。追踪LTCI和死亡记录至2023年12月;计算每月每10000人中的LTCI申请数和全因死亡数。COVID-19大流行期定义为从2020年3月开始,即世界卫生组织总干事于2020年3月11日将该情况定性为大流行之后。采用中断时间序列分段回归分析来比较大流行前(2018年1月 - 2020年2月)和大流行开始后(2020年3月 - 2023年12月)的趋势。

结果

从2018年1月到2023年12月,记录了4083份新的LTCI申请和2457例死亡。每月新的LTCI申请在大流行前呈适度上升趋势(每10000人中有0.4份,95%置信区间[CI]:0.1 - 0.8),在大流行开始时急剧下降(每10000人中有 - 9.6份,95% CI: - 16.0至 - 3.2),随后以高于大流行前水平的速率增加(每10000人中有0.8份,95% CI:0.6 - 1.0)。每月全因死亡数在大流行开始前后保持稳定,但在大流行后时期略有上升(每月每10000人中有0.3例,95% CI:0.2 - 0.5)。

结论

在本研究中,COVID-19大流行影响了新的LTCI申请和全因死亡率。在研究这些结果的队列研究中应仔细考虑这些影响。

相似文献

1
Impact of the COVID-19 Pandemic on New Long-term Care Insurance Applications and All-Cause Mortality in Older Adults in a Japanese Metropolitan Cohort: An Interrupted Time-Series Analysis.COVID-19大流行对日本大都市队列中老年人新长期护理保险申请和全因死亡率的影响:一项中断时间序列分析
J Epidemiol. 2025 May 3. doi: 10.2188/jea.JE20240464.
2
Prescription of Controlled Substances: Benefits and Risks管制药品的处方:益处与风险
3
Systemic corticosteroids for the treatment of COVID-19: Equity-related analyses and update on evidence.全身性皮质类固醇治疗 COVID-19:与公平相关的分析和证据更新。
Cochrane Database Syst Rev. 2022 Nov 17;11(11):CD014963. doi: 10.1002/14651858.CD014963.pub2.
4
Clinical Outcomes and Health Care Utilization in Patients with Advanced Chronic Kidney Disease not on Dialysis After the Onset of the COVID-19 Pandemic in Ontario, Canada.加拿大安大略省新冠疫情爆发后未接受透析治疗的晚期慢性肾病患者的临床结局与医疗保健利用情况
Can J Kidney Health Dis. 2025 Jul 3;12:20543581251350030. doi: 10.1177/20543581251350030. eCollection 2025.
5
Effects of city design on transport mode choice and exposure to health risks during and after a crisis: a retrospective observational analysis.危机期间及之后城市设计对交通方式选择和健康风险暴露的影响:一项回顾性观察分析
Lancet Planet Health. 2025 Jun;9(6):e467-e479. doi: 10.1016/S2542-5196(25)00088-9.
6
Estimating excess mortality during the COVID-19 pandemic from a population-based infectious disease surveillance in two diverse populations in Kenya, March 2020-December 2021.2020年3月至2021年12月期间,通过肯尼亚两个不同人群的基于人群的传染病监测来估算新冠疫情期间的超额死亡率。
PLOS Glob Public Health. 2023 Aug 23;3(8):e0002141. doi: 10.1371/journal.pgph.0002141. eCollection 2023.
7
Hyperimmune immunoglobulin for people with COVID-19.COVID-19 免疫球蛋白
Cochrane Database Syst Rev. 2023 Jan 26;1(1):CD015167. doi: 10.1002/14651858.CD015167.pub2.
8
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.系统性药理学治疗慢性斑块状银屑病:网络荟萃分析。
Cochrane Database Syst Rev. 2021 Apr 19;4(4):CD011535. doi: 10.1002/14651858.CD011535.pub4.
9
Risk of thromboembolism in patients with COVID-19 who are using hormonal contraception.COVID-19 患者使用激素避孕的血栓栓塞风险。
Cochrane Database Syst Rev. 2023 Jan 9;1(1):CD014908. doi: 10.1002/14651858.CD014908.pub2.
10
Convalescent plasma for people with COVID-19: a living systematic review.COVID-19 患者恢复期血浆治疗:一项实时系统评价。
Cochrane Database Syst Rev. 2023 May 10;5(5):CD013600. doi: 10.1002/14651858.CD013600.pub6.

本文引用的文献

1
Did the COVID-19 pandemic increase the long-term care insurance certification rate in Japan? An interrupted time-series analysis.新冠疫情是否提高了日本长期护理保险认证率?一项中断时间序列分析。
Geriatr Gerontol Int. 2025 Jul;25(7):983-985. doi: 10.1111/ggi.70061. Epub 2025 May 14.
2
Changes in Mortality During the COVID-19 Pandemic in Japan: Descriptive Analysis of National Health Statistics up to 2022.日本新冠疫情期间的死亡率变化:截至2022年的国家卫生统计描述性分析
J Epidemiol. 2025 Mar 5;35(3):154-159. doi: 10.2188/jea.JE20240158. Epub 2025 Jan 31.
3
How the prevalence of frailty shifted from 2022 to 2023 as the COVID-19 pandemic calmed down in Japan: second report.
随着新冠疫情在日本趋于平稳,2022年至2023年期间虚弱症患病率如何变化:第二次报告。
J Nutr Health Aging. 2024 Jul;28(7):100254. doi: 10.1016/j.jnha.2024.100254. Epub 2024 Apr 29.
4
Prevalence and factors associated with changes in frailty among community-dwelling older adults in Japan during the COVID-19 pandemic: A prospective cohort study from 2020 to 2022.在 COVID-19 大流行期间,日本社区居住的老年人虚弱程度变化的流行率及相关因素:一项 2020 年至 2022 年的前瞻性队列研究。
Geriatr Gerontol Int. 2024 Jan;24(1):40-47. doi: 10.1111/ggi.14748. Epub 2023 Nov 27.
5
Impact of the COVID-19 pandemic on mortality trends in Japan: a reversal in 2021? A descriptive analysis of national mortality data, 1995-2021.**标题**:COVID-19 大流行对日本死亡率趋势的影响:2021 年出现逆转?1995-2021 年全国死亡率数据的描述性分析。
BMJ Open. 2023 Aug 31;13(8):e071785. doi: 10.1136/bmjopen-2023-071785.
6
Changes in physical and social activities among community-dwelling Japanese older adults during three years of the COVID-19 pandemic.COVID-19大流行三年期间日本社区居住老年人身体和社交活动的变化
Geriatr Gerontol Int. 2024 Mar;24 Suppl 1:395-396. doi: 10.1111/ggi.14645. Epub 2023 Jul 23.
7
Frailty under COVID-19 pandemic in Japan: Changes in prevalence of frailty from 2017 to 2021.日本 COVID-19 大流行期间的衰弱症:2017 年至 2021 年衰弱症患病率的变化。
J Am Geriatr Soc. 2023 May;71(5):1603-1609. doi: 10.1111/jgs.18237. Epub 2023 Jan 17.
8
Association Between Life Expectancy at Age 60 Years Before the COVID-19 Pandemic and Excess Mortality During the Pandemic in Aging Countries.新冠疫情大流行之前60岁时的预期寿命与老龄化国家疫情期间超额死亡率之间的关联
JAMA Netw Open. 2022 Oct 3;5(10):e2237528. doi: 10.1001/jamanetworkopen.2022.37528.
9
Impact of the First-Fourth Waves of the COVID-19 Pandemic on New Applications for Long-term Care Insurance in a Metropolitan Area of Japan.新冠疫情第一至第四波对日本某大都市长期护理保险新申请的影响。
J Epidemiol. 2022 Nov 5;32(11):524-526. doi: 10.2188/jea.JE20220084. Epub 2022 Sep 30.
10
The Influence of the COVID-19 Pandemic on Physical Activity and New Incidence of Frailty among Initially Non-Frail Older Adults in Japan: A Follow-Up Online Survey.《COVID-19 大流行对日本最初非虚弱老年人身体活动和新虚弱发生率的影响:一项后续在线调查》
J Nutr Health Aging. 2021;25(6):751-756. doi: 10.1007/s12603-021-1634-2.