Ringenberg Q S
Med Pediatr Oncol. 1985;13(5):301-6. doi: 10.1002/mpo.2950130510.
Tumors of unknown origin (TUOs) account for 3% of cancers and represent the eighth-most common cancer diagnosis. Although TUOs are commonly classified by their histological presentation, examination of the location of the metastases is equally important. When the histological type and location of metastases are both known, a finite number of common clinical syndromes emerge and one can predict the most common occult primaries.
原发灶不明肿瘤（TUO）占癌症的3%，是第八大最常见的癌症诊断类型。尽管TUO通常根据其组织学表现进行分类，但对转移灶位置的检查同样重要。当转移灶的组织学类型和位置都已知时，会出现有限数量的常见临床综合征，并且可以预测最常见的隐匿性原发肿瘤。
