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6MV真直线加速器中快速弧形放疗与调强放疗的比较:AAPM TG-119测试在治疗计划和质量保证中的应用

Comparison of Rapid Arc and Intensity Modulated Radiotherapy in a True Beam Linear Accelerator for 6 MV: Application of AAPM TG-119 tests in treatment planning and quality assurance.

作者信息

Roy Soumya, Sarkar Biplab, Pradhan Anirudh

机构信息

GLA University Mathura Uttar Pradesh India.

Chief Medical Physicist, Department of Radiation Oncology Manipal Hospital, Dwarka New Delhi India.

出版信息

Precis Radiat Oncol. 2023 Nov 29;7(4):256-267. doi: 10.1002/pro6.1212. eCollection 2023 Dec.

DOI:10.1002/pro6.1212
PMID:40336866
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11935083/
Abstract

OBJECTIVE

We developed rapid arc (RA) and intensity-modulated radiotherapy (IMRT) plans based on the American Association of Physicists in Medicine Task Group-119 (AAPM TG-119) proposals and compared the planning and quality assurance results.

MATERIALS AND METHODS

Two treatment plans were used for each study patient: one using 7-9 IMRT fields and the other using the two full-arc RA methods. Plan optimization and dose calculations were performed using 6 MV photons and Eclipse with the anisotropic analytical algorithm (AAA). Task group (TG)-119 described the planning objectives used to evaluate the treatment plans generated for this study. Point dose, planar fluence measurement, and trajectory log file analysis are used for quality assurance.

RESULTS

The conformity index (CI) for treatment plans varied between 0.76-0.91 when using IMRT and 0.75-0.93 when using RA. The homogeneity index (HI) was approximately 0.10-0.24 (IMRT) and 0.07-0.23 (RA). The ratio of the total number of monitor units required for IMRT to that required for RA was between 0.87 and 2.14. The treatment log files exhibited higher gamma passing with RA than with IMRT.

CONCLUSION

RA plans were more effective than IMRT plans in achieving the test goals. Point dose measurements and electronic portal imaging device (EPID)-based planar fluence measurements showed statistically insignificant differences between the IMRT and RA plan quality assurance (QA) results. However, the trajectory log file analysis exhibited better gamma-passing results for RA than for IMRT.

摘要

目的

我们根据美国医学物理学家协会任务组119(AAPM TG - 119)的建议制定了容积旋转调强放疗(RA)和调强放疗(IMRT)计划,并比较了计划制定和质量保证结果。

材料与方法

对每位研究患者使用两种治疗计划:一种使用7 - 9个IMRT射野,另一种使用两种全弧RA方法。使用6兆伏光子和采用各向异性解析算法(AAA)的Eclipse进行计划优化和剂量计算。任务组(TG)- 119描述了用于评估本研究生成的治疗计划的计划目标。点剂量、平面注量测量和轨迹日志文件分析用于质量保证。

结果

使用IMRT时治疗计划的适形指数(CI)在0.76 - 0.91之间,使用RA时在0.75 - 0.93之间。均匀性指数(HI)约为0.10 - 0.24(IMRT)和0.07 - 0.23(RA)。IMRT所需的监测单位总数与RA所需的监测单位总数之比在0.87至2.14之间。治疗日志文件显示RA的γ通过率高于IMRT。

结论

在实现测试目标方面,RA计划比IMRT计划更有效。点剂量测量和基于电子射野影像装置(EPID)的平面注量测量显示,IMRT和RA计划质量保证(QA)结果之间的差异无统计学意义。然而,轨迹日志文件分析显示RA的γ通过率比IMRT更好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acc5/11935083/7c9c1e0afc03/PRO6-7-256-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acc5/11935083/cfa02e230334/PRO6-7-256-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acc5/11935083/d1105b8bb213/PRO6-7-256-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acc5/11935083/0f7b45b2c3ea/PRO6-7-256-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acc5/11935083/807ac34c7f82/PRO6-7-256-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acc5/11935083/9328d0344714/PRO6-7-256-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acc5/11935083/7c9c1e0afc03/PRO6-7-256-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acc5/11935083/cfa02e230334/PRO6-7-256-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acc5/11935083/d1105b8bb213/PRO6-7-256-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acc5/11935083/0f7b45b2c3ea/PRO6-7-256-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acc5/11935083/807ac34c7f82/PRO6-7-256-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acc5/11935083/9328d0344714/PRO6-7-256-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/acc5/11935083/7c9c1e0afc03/PRO6-7-256-g003.jpg

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本文引用的文献

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Dosimetric Evaluation of Volumetric Modulated Arc Therapy (VMAT) and Intensity Modulated Radiotherapy (IMRT) Using AAPM TG 119 Protocol.使用美国医学物理学家协会(AAPM)TG 119协议对容积调强弧形放疗(VMAT)和调强放疗(IMRT)进行剂量学评估。
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Application of AAPM TG 119 to volumetric arc therapy (VMAT).AAPM TG119 在容积弧形调强放疗(VMAT)中的应用。
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IMRT commissioning: multiple institution planning and dosimetry comparisons, a report from AAPM Task Group 119.调强适形放疗的验证:多机构计划和剂量学比较,AAPM 工作组 119 报告
Med Phys. 2009 Nov;36(11):5359-73. doi: 10.1118/1.3238104.
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A comparison of volumetric modulated arc therapy and conventional intensity-modulated radiotherapy for frontal and temporal high-grade gliomas.容积旋转调强弧形治疗与常规强度调制放射治疗在前额和颞叶高级别胶质瘤中的比较。
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