Zhang Hui, Zhang Zhen, Yuan Shuanghu
Department of Radiation Oncology Fudan University Shanghai Cancer Center Shanghai China.
China Anti-Cancer Association Tumor Support Therapy Committee.
Precis Radiat Oncol. 2023 Dec 25;7(4):237-255. doi: 10.1002/pro6.1217. eCollection 2023 Dec.
Although radiotherapy plays an important role in the treatment of cancer, it may have negative effects in some individuals. Rectal injury is a common adverse effect of abdominal and pelvic radiotherapy. This injury is caused by administering radiation to the abdomen. Appropriate treatment techniques can be determined if doctors have a better understanding of the incidence, risk factors, and clinical symptoms of radiation-induced rectal injuries. Studies on the underlying pathophysiology of radiation-induced rectal injury may aid in the development of effective treatment and prevention strategies. The implementation of efficient preventive measures can improve the quality of life of patients with cancer and make it easier for them to complete their treatment. Therefore, comprehensive and accurate assessments are crucial for developing holistic and individualized treatment plans for patients who have already developed symptoms, with early intervention being a priority.
尽管放射治疗在癌症治疗中起着重要作用，但在某些个体中可能会产生负面影响。直肠损伤是腹部和盆腔放射治疗的常见不良反应。这种损伤是由于对腹部进行辐射所致。如果医生能更好地了解放射性直肠损伤的发生率、危险因素和临床症状，就可以确定合适的治疗技术。对放射性直肠损伤潜在病理生理学的研究可能有助于制定有效的治疗和预防策略。实施有效的预防措施可以提高癌症患者的生活质量，使他们更容易完成治疗。因此，对于已经出现症状的患者，全面准确的评估对于制定整体和个性化的治疗方案至关重要，早期干预是重中之重。
