Radiation-induced bladder injury is a common complication after pelvic radiotherapy. Few studies exist on diagnosing and treating radiation-induced bladder injury, with no established guidelines or consensus in China or internationally. Clinical physicians' diagnosis and treatment of radiation-induced bladder injury are primarily based on their own clinical experience, and there is an urgent need for unified guidelines to standardize clinical diagnosis and treatment. Therefore, the Chinese Radiation Therapy Oncology Group, China Anti-Cancer Association Tumor Support Therapy Committee, and China Anti-Cancer Association Tumor Radiation Protection Committee gathered experts to develop Chinese clinical practice guidelines, guiding diagnosing and treating radiation-induced bladder injury. The development of these guidelines adopted the grading system of evidence quality and recommendation strength (GRADE).