Fan Ming, Feng Mei, Yuan Shuanghu
China Anti-Cancer Association Tumor Support Therapy Committee.
China Anti-Cancer Association Tumor Radiation Protection Committee.
Precis Radiat Oncol. 2023 Sep 10;7(3):160-172. doi: 10.1002/pro6.1208. eCollection 2023 Sep.
Radiation-induced dermatitis is one of the most prevalent complications in patients undergoing cancer radiotherapy and poses a significant challenge to cancer therapy. The symptoms include erythema, dry desquamation, and moist desquamation, which are frequently observed in patients with breast, head and neck, anal, and vulvar cancers. Early skin reactions typically manifest within 2-4 weeks following the initiation of radiotherapy. In severe cases, acute dermatitis can cause radiotherapy interruptions, prolong treatment time, and ultimately affect patient outcomes and quality of life. Currently, there are numerous guidelines on radiation dermatitis, including the Multinational Association of Supportive Care in Cancer (MASCC), British Columbia Cancer Agency (BCCA), Oncology Nursing Society (ONS), and UK Society of Radiographers (SCoR) guidelines. In China, dermatology experts have drafted a consensus. However, due to the differing backgrounds of experts, recommendations among guidelines vary. These guidelines were first developed by Chinese radiation oncologists. The evidence-based guideline in this paper fully considers and adopts China's national conditions; hence, it can be easily applied in daily practice.
放射性皮炎是癌症放疗患者中最常见的并发症之一,对癌症治疗构成重大挑战。症状包括红斑、干性脱屑和湿性脱屑,在乳腺癌、头颈癌、肛门癌和外阴癌患者中经常出现。早期皮肤反应通常在放疗开始后的2 - 4周内出现。在严重情况下,急性皮炎会导致放疗中断、延长治疗时间,并最终影响患者的治疗效果和生活质量。目前,关于放射性皮炎有许多指南,包括癌症支持治疗多国协会(MASCC)、不列颠哥伦比亚癌症机构(BCCA)、肿瘤护理学会(ONS)和英国放射技师协会(SCoR)的指南。在中国,皮肤科专家已经起草了一项共识。然而,由于专家背景不同,各指南之间的建议存在差异。这些指南最初是由中国放射肿瘤学家制定的。本文基于循证的指南充分考虑并采用了中国国情,因此可以很容易地应用于日常实践。