Parvizi Arman, Pour Mohammad Reza, Haddadi Soudabeh, Kia Shaghayegh Rezaei, Akbari Maryam, Yazdanipour Mohammad Ali
Anesthesiology Research Center, Department of Anesthesiology, Alzahra Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Department of Operating Room and Anesthesia, Langrood Paramedical School, Guilan University of Medical Sciences, Rasht, Iran.
Ann Med Surg (Lond). 2025 Apr 10;87(5):2689-2695. doi: 10.1097/MS9.0000000000003032. eCollection 2025 May.
The present study aims to determine the effect of peppermint essential oil on postoperative nausea, vomiting, and pain in rhinoplasty patients.
This randomized clinical trial included 80 patients aged 18-65 randomly assigned to either the peppermint or the control group. The peppermint group received 20 oral drops of 2% peppermint essence 30 minutes before surgery, while the control group received an equal amount of distilled water. Blinding was maintained for recovery staff and patients. Nausea, vomiting, and pain were assessed at three intervals: upon entry into the recovery room, upon ward admission, and one-hour post-admission, using the Visual Analogue Scale (VAS) and observational methods.
The evaluation of pain and vomiting in patients during recovery, upon ward admission, and one-hour post-admission did not reveal a statistically significant difference between the two intervention groups (those administered with peppermint essence and the control group) ( > 0.05). However, a statistically significant association was observed between nausea at different measurement times and the groups under study ( < 0.001). Specifically, at all three measurement times, the incidence of nausea was significantly lower in patients who were administered mint compared to those in the control group. Nevertheless, intra-group comparisons did not reveal a significant difference in the occurrence of nausea across different measurement times ( > 0.05).
The application of peppermint essential oil is efficacious in mitigating postoperative nausea following rhinoplasty. Consequently, peppermint can be considered a safe and effective antiemetic intervention in the surgical setting.
本研究旨在确定薄荷精油对隆鼻手术患者术后恶心、呕吐及疼痛的影响。
这项随机临床试验纳入了80名年龄在18至65岁之间的患者,他们被随机分配至薄荷组或对照组。薄荷组在手术前30分钟口服20滴2%的薄荷精华液,而对照组则服用等量的蒸馏水。对恢复室工作人员和患者维持盲法。使用视觉模拟量表(VAS)和观察方法,在三个时间点评估恶心、呕吐和疼痛情况:进入恢复室时、病房入院时及入院后1小时。
在恢复期间、病房入院时及入院后1小时对患者的疼痛和呕吐情况进行评估,结果显示两个干预组(给予薄荷精华液的组和对照组)之间无统计学显著差异(>0.05)。然而,在不同测量时间的恶心情况与所研究的组之间观察到有统计学显著关联(<0.001)。具体而言,在所有三个测量时间点,服用薄荷的患者恶心发生率均显著低于对照组。尽管如此,组内比较未显示不同测量时间的恶心发生率有显著差异(>0.05)。
薄荷精油的应用在减轻隆鼻术后恶心方面是有效的。因此,薄荷可被视为手术环境中一种安全有效的止吐干预措施。