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To irradiate or electroporate: how should we ablate pancreatic cancer?

作者信息

Bryant John Michael, Nakashima Justyn, Khatri Vaseem, Malafa Mokenge, Frakes Jessica, Hoffe Sarah

机构信息

Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

Department of Gastrointestinal Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

出版信息

Transl Gastroenterol Hepatol. 2025 Apr 17;10:19. doi: 10.21037/tgh-24-164. eCollection 2025.

DOI:10.21037/tgh-24-164
PMID:40337766
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12056099/
Abstract
摘要

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本文引用的文献

1
Integrating IL-12 mRNA nanotechnology with SBRT eliminates T cell exhaustion in preclinical models of pancreatic cancer.将白细胞介素-12信使核糖核酸纳米技术与立体定向体部放疗相结合，可消除胰腺癌临床前模型中的T细胞耗竭。
Mol Ther Nucleic Acids. 2024 Sep 30;35(4):102350. doi: 10.1016/j.omtn.2024.102350. eCollection 2024 Dec 10.
2
Ablative treatments for locally advanced pancreatic cancer: the CROSSFIRE trial.
Lancet Gastroenterol Hepatol. 2024 Aug;9(8):687. doi: 10.1016/S2468-1253(24)00130-4.
3
Ablative treatments for locally advanced pancreatic cancer: the CROSSFIRE trial: Authors' reply.
Lancet Gastroenterol Hepatol. 2024 Aug;9(8):687-688. doi: 10.1016/S2468-1253(24)00162-6.
4
Structure-specific rigid dose accumulation dosimetric analysis of ablative stereotactic MRI-guided adaptive radiation therapy in ultracentral lung lesions.超中央型肺部病变的立体定向MRI引导下适形放射治疗中结构特异性刚性剂量累积剂量学分析
Commun Med (Lond). 2024 May 22;4(1):96. doi: 10.1038/s43856-024-00526-7.
5
MRI-guided stereotactic ablative body radiotherapy versus CT-guided percutaneous irreversible electroporation for locally advanced pancreatic cancer (CROSSFIRE): a single-centre, open-label, randomised phase 2 trial.MRI 引导下立体定向消融体放射治疗与 CT 引导下经皮不可逆电穿孔治疗局部晚期胰腺癌（CROSSFIRE）：一项单中心、开放标签、随机 2 期临床试验。
Lancet Gastroenterol Hepatol. 2024 May;9(5):448-459. doi: 10.1016/S2468-1253(24)00017-7. Epub 2024 Mar 19.
6
Stereotactic MR-guided on-table adaptive radiation therapy (SMART) for borderline resectable and locally advanced pancreatic cancer: A multi-center, open-label phase 2 study.立体定向磁共振引导下术中自适应放疗（SMART）治疗局部进展期和局部可切除胰腺癌的多中心、开放标签Ⅱ期研究。
Radiother Oncol. 2024 Feb;191:110064. doi: 10.1016/j.radonc.2023.110064. Epub 2023 Dec 20.
7
Stereotactic Magnetic Resonance-Guided Adaptive and Non-Adaptive Radiotherapy on Combination MR-Linear Accelerators: Current Practice and Future Directions.基于磁共振线性加速器组合的立体定向磁共振引导自适应与非自适应放射治疗：当前实践与未来方向。
Cancers (Basel). 2023 Mar 30;15(7):2081. doi: 10.3390/cancers15072081.
8
Multi-Institutional Outcomes of Patients Aged 75 years and Older With Pancreatic Ductal Adenocarcinoma Treated With 5-Fraction Ablative Stereotactic Magnetic Resonance Image-Guided Adaptive Radiation Therapy (A-SMART).75 岁及以上胰腺导管腺癌患者接受 5 分次消融性立体定向磁共振图像引导自适应放疗（A-SMART）的多机构治疗结果。
Cancer Control. 2023 Jan-Dec;30:10732748221150228. doi: 10.1177/10732748221150228.
9
Surgical and Pathologic Outcomes of Pancreatic Adenocarcinoma (PA) After Preoperative Ablative Stereotactic Magnetic Resonance Image Guided Adaptive Radiation Therapy (A-SMART).术前立体定向磁共振图像引导自适应放射治疗（A-SMART）后胰腺腺癌（PA）的手术及病理结果
Adv Radiat Oncol. 2022 Aug 6;7(6):101045. doi: 10.1016/j.adro.2022.101045. eCollection 2022 Nov-Dec.
10
Multicenter randomized controlled trial and registry study to assess the safety and efficacy of the NanoKnife® system for the ablation of stage 3 pancreatic adenocarcinoma: overview of study protocols.多中心随机对照试验和登记研究评估 NanoKnife®系统治疗 3 期胰腺腺癌的安全性和有效性：研究方案概述。
BMC Cancer. 2021 Jul 7;21(1):785. doi: 10.1186/s12885-021-08474-4.