Bansal Agam, Nandan Anirudh, Sroubek Jakub, Lee Justin, Higuchi Koji, Hussein Ayman, Nakhla Shady, Chung Mina, Varma Niraj, Saliba Walid, Bhargava Mandeep, Taigen Tyler, Kanj Mohamed, Wazni Oussama, Santangeli Pasquale
Cardiac Electrophysiology Section, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
Cardiac Electrophysiology Section, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
JACC Clin Electrophysiol. 2025 Jul;11(7):1453-1461. doi: 10.1016/j.jacep.2025.02.041. Epub 2025 May 8.
Existing studies have shown a relationship between hospital case volume and outcomes of various cardiovascular procedures. The impact of hospital procedure volume on complications of catheter ablation of ventricular tachycardia (VT) and the potential benefit of selective referral to high-volume centers have not been previously evaluated.
This study sought to assess the associations between hospital procedure volume of VT catheter ablation and postprocedural morbidity and mortality.
The NIS (National Inpatient Sample) database was queried for hospital admissions for VT ablation in the United States during the year 2019. Hospitals were divided into tertiles of VT ablation volume (high-volume hospitals [HVH] ≥50 ablations per year, medium-volume hospitals performed 16-49 ablations, and low-volume hospitals [LVH] ≤ 15 ablations). Data on adverse events including in-hospital mortality and postprocedural complications were collected.
Patients in HVH were more likely to have comorbidities including heart failure (74.3% vs 64.7%; P = 0.02) and kidney disease (25.3% vs 21.7%; P = 0.044) than LVH. After controlling for baseline confounders and with LVH as reference, HVH had lower in-hospital mortality (adjusted OR [aOR]: 0.80; 95% CI: 0.71-0.91; P = 0.04), cardiac tamponade (aOR: 0.58; 95% CI: 0.32-0.78; P = 0.01), and need for blood transfusion (aOR: 0.41; 95% CI: 0.21-0.68; P = 0.008). It can be estimated that for every 17 patients shifted from LVH to HVH, 1 death, cardiac tamponade, or major bleeding event could be prevented.
Patients undergoing VT ablation at HVH were sicker on average, yet had lower in-hospital mortality and procedure-related morbidity compared to LVH. Selective VT patient referral to HVH has the potential to substantially reduce in-hospital complications following VT ablation nationally.
现有研究表明,医院病例数量与各种心血管手术的结果之间存在关联。此前尚未评估医院手术量对室性心动过速(VT)导管消融并发症的影响以及选择性转诊至高手术量中心的潜在益处。
本研究旨在评估VT导管消融的医院手术量与术后发病率和死亡率之间的关联。
查询2019年美国国家住院样本(NIS)数据库中VT消融的住院病例。医院被分为VT消融量的三个等级(高手术量医院[HVH]每年≥50例消融,中等手术量医院进行16 - 49例消融,低手术量医院[LVH]≤15例消融)。收集包括住院死亡率和术后并发症在内的不良事件数据。
与LVH相比,HVH的患者更易合并心力衰竭(74.3%对64.7%;P = 0.02)和肾病(25.3%对21.7%;P = 0.044)等合并症。在控制基线混杂因素并以LVH为参照后,HVH的住院死亡率较低(调整后比值比[aOR]:0.80;95%置信区间:0.71 - 0.91;P = 0.04)、心包填塞发生率较低(aOR:0.58;95%置信区间:0.32 - 0.78;P = 0.01)以及输血需求较低(aOR:0.41;95%置信区间:0.21 - 0.68;P = 0.008)。据估计,每将17例患者从LVH转诊至HVH,可预防1例死亡、心包填塞或大出血事件。
在HVH接受VT消融的患者平均病情更重,但与LVH相比,其住院死亡率和手术相关发病率较低。将VT患者选择性转诊至HVH有可能在全国范围内大幅降低VT消融后的住院并发症。