Hassenstein E, Rhomberg W
Med Klin. 1977 Feb 4;72(5):171-5.
In a clinical randomized trial of 40 patients with inoperable lung carcinoma the success of radiotherapy alone (5000 rads) was compared with a combined modality with radiotherapy (5000 rads) and ICRF 159 (250 mg p.d.). There was no difference in survival rates but haematological toxicity (leucocytes, erythrocytes, platelets and haemoglobin) was marked in patients with combined treatment. In patients with oat-cell-carcinoma survival rates seem to be better after combination therapy.
在一项针对40例无法手术的肺癌患者的临床随机试验中，对比了单纯放疗（5000拉德）与放疗（5000拉德）联合ICRF 159（每日250毫克）的综合治疗方式的效果。生存率没有差异，但综合治疗的患者血液学毒性（白细胞、红细胞、血小板和血红蛋白）较为明显。对于燕麦细胞癌患者，联合治疗后的生存率似乎更高。
