Schultz Alison M, Creger Paul E, Mathews Trey J, Minshall Christian T, Lombardozzi Kristine A
Edward Via College of Osteopathic Medicine, Spartanburg, SC, USA.
Division of Surgery, Spartanburg Medical Center, Spartanburg, SC, USA.
Am Surg. 2025 Aug;91(8):1378-1387. doi: 10.1177/00031348251342076. Epub 2025 May 9.
Congenital peritoneal encapsulation (CPE), a rare developmental anomaly in which the small intestines are enclosed within an accessory peritoneal sac, is an uncommon but important cause of abdominal pain and small bowel obstruction. With fewer than 60 reported cases, the demographics, imaging findings, and symptoms of CPE remain elusive, as most cases are diagnosed intraoperatively during treatment for bowel obstruction. We report a case of a 34-year-old male with no significant medical history who presented with acute abdominal pain and nausea. He was hemodynamically stable and afebrile, and CT imaging indicated a possible small bowel obstruction. Surgical intervention was required when his condition worsened, with large-volume emesis following oral contrast administration during a small bowel follow-through study. Explorative laparotomy revealed a peritoneal encapsulation of the entire small bowel as the cause of obstruction. Complete removal of the membrane was performed, and histopathology confirmed findings consistent with an intraperitoneal sac with reactive changes, supporting the diagnosis of CPE. This review highlights the challenges in diagnosing CPE due to its lack of associated comorbidities, minimal symptoms, and nonspecific imaging findings. A detailed discussion of 21 recent cases of CPE emphasizes patient demographics, presentation history, imaging, physical exam, intraoperative findings, and surgical management. This modern analysis underscores the importance of considering CPE in the differential diagnosis for unexplained abdominal pain or bowel obstruction, particularly when conventional diagnostic methods fail to identify a cause.
先天性腹膜包裹症(CPE)是一种罕见的发育异常,其中小肠被包裹在一个副腹膜囊内,是腹痛和小肠梗阻的一个不常见但重要的原因。由于报告的病例少于60例,CPE的人口统计学特征、影像学表现和症状仍然难以捉摸,因为大多数病例是在肠梗阻治疗的手术过程中被诊断出来的。我们报告一例34岁男性,无重大病史,表现为急性腹痛和恶心。他血流动力学稳定,无发热,CT成像显示可能存在小肠梗阻。在小肠通过造影检查口服造影剂后出现大量呕吐,病情恶化,需要进行手术干预。剖腹探查发现整个小肠被腹膜包裹是梗阻的原因。完整切除包膜,组织病理学证实结果与有反应性改变的腹膜囊一致,支持CPE的诊断。本综述强调了由于CPE缺乏相关合并症、症状轻微和影像学表现不特异,在诊断上存在挑战。对21例近期CPE病例的详细讨论强调了患者的人口统计学特征、病史、影像学、体格检查、术中发现和手术管理。这种现代分析强调了在不明原因腹痛或肠梗阻的鉴别诊断中考虑CPE的重要性,特别是当传统诊断方法未能找出病因时。