• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

阿尔及利亚南部农村沙漠地区的脑瘫:合并症和未满足需求的流行病学横断面研究

Cerebral Palsy in a Rural Desert Population of Southern Algeria: A Cross-Sectional Study of Epidemiology of Comorbidities and Unmet Needs.

作者信息

Bonezzi Linda, Accorinti Ilaria, Papoff Francesca Maria Agostina, Orsi Maria, D'Arcangelo Giacomo, Bartolini Emanuele, Battini Roberta

机构信息

Department of Neuroscience, IRCCS Stella Maris Foundation, Pisa, Italy.

Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.

出版信息

J Child Neurol. 2025 Oct;40(9):757-766. doi: 10.1177/08830738251336486. Epub 2025 May 8.

DOI:10.1177/08830738251336486
PMID:40340658
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12414107/
Abstract

BackgroundCerebral palsy is a group of nonprogressive motor disorders resulting from early brain development impairment. Its prevalence is higher in low- and middle-income countries, where health care resources are limited. Data on cerebral palsy in refugee settings remain scarce, particularly in regions marked by prolonged displacement.MethodsThis cross-sectional study examined 29 children with cerebral palsy in the Sahrawi refugee camps in Tindouf, Algeria. Detailed demographic, medical history, neurological findings, and comorbidity data were collected during outpatient visits conducted as part of a humanitarian mission.ResultsPerinatal distress was reported in 65.5% of cases. Motor impairments were significant, with only 44.8% able to walk and 20.7% lacking head control. Language delays (65.5%), feeding difficulties (65.5%), and epilepsy (52%) were highly prevalent. Diagnostic evaluations, such as magnetic resonance imaging (MRI) and electroencephalography (EEG), were scarce and inconsistent. Access to rehabilitation services was discontinuous, and pharmacologic treatments for spasticity and pain were unavailable. Environmental factors, such as sandy terrain, further complicated mobility.ConclusionCerebral palsy in the Sahrawi refugee camps reflects patterns seen in low- and middle-income countries but is exacerbated by displacement and resource scarcity. Improved access to early diagnosis, structured rehabilitation, and targeted pharmacologic therapies is urgently needed to address these unmet needs and improve outcomes for affected children.

摘要

背景

脑瘫是一组因早期脑发育受损而导致的非进行性运动障碍。在医疗资源有限的低收入和中等收入国家,其患病率更高。关于难民环境中脑瘫的数据仍然稀少,特别是在长期流离失所的地区。

方法

这项横断面研究对阿尔及利亚廷杜夫撒哈拉难民营中的29名脑瘫儿童进行了检查。作为人道主义任务的一部分,在门诊就诊期间收集了详细的人口统计学、病史、神经学检查结果和合并症数据。

结果

65.5%的病例报告有围产期窘迫。运动障碍严重,只有44.8%的儿童能够行走,20.7%的儿童头部控制能力缺失。语言发育迟缓(65.5%)、喂养困难(65.5%)和癫痫(52%)非常普遍。磁共振成像(MRI)和脑电图(EEG)等诊断评估很少且不一致。康复服务的获取不连续,且没有针对痉挛和疼痛问题的药物治疗。沙地地形等环境因素使行动更加困难。

结论

撒哈拉难民营中的脑瘫情况反映了低收入和中等收入国家的常见模式,但因流离失所和资源匮乏而加剧。迫切需要改善早期诊断、结构化康复和有针对性的药物治疗的可及性,以满足这些未得到满足的需求并改善受影响儿童的治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4b/12414107/c51863458239/10.1177_08830738251336486-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4b/12414107/d0fbfd21b041/10.1177_08830738251336486-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4b/12414107/a1c5d75d2618/10.1177_08830738251336486-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4b/12414107/c51863458239/10.1177_08830738251336486-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4b/12414107/d0fbfd21b041/10.1177_08830738251336486-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4b/12414107/a1c5d75d2618/10.1177_08830738251336486-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4b/12414107/c51863458239/10.1177_08830738251336486-fig3.jpg

相似文献

1
Cerebral Palsy in a Rural Desert Population of Southern Algeria: A Cross-Sectional Study of Epidemiology of Comorbidities and Unmet Needs.阿尔及利亚南部农村沙漠地区的脑瘫:合并症和未满足需求的流行病学横断面研究
J Child Neurol. 2025 Oct;40(9):757-766. doi: 10.1177/08830738251336486. Epub 2025 May 8.
2
Intrathecal baclofen for treating spasticity in children with cerebral palsy.鞘内注射巴氯芬治疗小儿脑性瘫痪痉挛状态
Cochrane Database Syst Rev. 2015 Nov 13;2015(11):CD004552. doi: 10.1002/14651858.CD004552.pub2.
3
Speech and language therapy to improve the communication skills of children with cerebral palsy.言语和语言治疗以提高脑瘫患儿的沟通能力。
Cochrane Database Syst Rev. 2004;2004(2):CD003466. doi: 10.1002/14651858.CD003466.pub2.
4
Association of Gestational Age at Birth and Changes on MRI With Prevalence and Spectrum of Comorbidities in Children With Cerebral Palsy.出生时胎龄与 MRI 变化与脑瘫儿童合并症的患病率和谱的关系。
Neurology. 2024 Jul 23;103(2):e209571. doi: 10.1212/WNL.0000000000209571. Epub 2024 Jun 18.
5
Trihexyphenidyl for dystonia in cerebral palsy.用于治疗脑瘫肌张力障碍的苯海索
Cochrane Database Syst Rev. 2018 May 15;5(5):CD012430. doi: 10.1002/14651858.CD012430.pub2.
6
Prescription of Controlled Substances: Benefits and Risks管制药品的处方:益处与风险
7
Exercise interventions for cerebral palsy.脑瘫的运动干预
Cochrane Database Syst Rev. 2017 Jun 11;6(6):CD011660. doi: 10.1002/14651858.CD011660.pub2.
8
Prevalence of Leishmania infection in refugee camps: A serological and molecular study in Gambella and Benishangul-Gumuz, Ethiopia.难民营中利什曼原虫感染的患病率:埃塞俄比亚甘贝拉和本尚古勒-古穆兹的血清学和分子研究
PLoS Negl Trop Dis. 2025 Jul 8;19(7):e0013280. doi: 10.1371/journal.pntd.0013280. eCollection 2025 Jul.
9
Antenatal and intrapartum interventions for preventing cerebral palsy: an overview of Cochrane systematic reviews.预防脑瘫的产前和产时干预措施:Cochrane系统评价概述
Cochrane Database Syst Rev. 2017 Aug 8;8(8):CD012077. doi: 10.1002/14651858.CD012077.pub2.
10
Pharmacological treatment of children with gastro-oesophageal reflux.胃食管反流患儿的药物治疗
Cochrane Database Syst Rev. 2014 Nov 24;2014(11):CD008550. doi: 10.1002/14651858.CD008550.pub2.

本文引用的文献

1
Pharmacological and neurosurgical management of cerebral palsy and dystonia: Clinical practice guideline update.脑性瘫痪和肌张力障碍的药理学及神经外科治疗:临床实践指南更新
Dev Med Child Neurol. 2024 Sep;66(9):1133-1147. doi: 10.1111/dmcn.15921. Epub 2024 Apr 19.
2
Global prevalence of cerebral palsy: A systematic analysis.全球脑瘫患病率:系统分析。
Dev Med Child Neurol. 2022 Dec;64(12):1494-1506. doi: 10.1111/dmcn.15346. Epub 2022 Aug 11.
3
'There is family tension, but they understand…': familial and sibling relationships following the diagnosis of cerebral palsy in children in Ghana.
“存在家庭紧张关系,但他们理解……”:加纳儿童被诊断出患有脑瘫后的家庭及兄弟姐妹关系
Int J Dev Disabil. 2019 Feb 10;68(1):35-46. doi: 10.1080/20473869.2019.1573572. eCollection 2022.
4
Outcome of Community-Based Early Intervention and Rehabilitation for Children with Cerebral Palsy in Rural Bangladesh: A Quasi-Experimental Study.孟加拉国农村地区脑瘫儿童社区早期干预与康复的效果:一项准实验研究
Brain Sci. 2021 Sep 10;11(9):1189. doi: 10.3390/brainsci11091189.
5
Functional development in children with cerebral palsy in Uganda: population-based longitudinal cohort study.乌干达脑瘫儿童的功能发育:基于人群的纵向队列研究。
Dev Med Child Neurol. 2022 Jan;64(1):70-79. doi: 10.1111/dmcn.14996. Epub 2021 Aug 4.
6
Cerebral Palsy: Current Opinions on Definition, Epidemiology, Risk Factors, Classification and Treatment Options.脑瘫:关于定义、流行病学、风险因素、分类及治疗选择的当前观点
Neuropsychiatr Dis Treat. 2020 Jun 12;16:1505-1518. doi: 10.2147/NDT.S235165. eCollection 2020.
7
A Cross-sectional Study of the Clinical Profile of Children With Cerebral Palsy in Benin, a West African Low-Income Country.一项针对西非低收入国家贝宁脑瘫患儿临床特征的横断面研究。
J Child Neurol. 2019 Nov;34(13):842-850. doi: 10.1177/0883073819864516. Epub 2019 Jul 24.
8
Hip Surveillance in Children With Cerebral Palsy.脑瘫儿童的髋关节监测。
J Am Acad Orthop Surg. 2019 Oct 15;27(20):760-768. doi: 10.5435/JAAOS-D-18-00184.
9
Genetic mimics of cerebral palsy.脑性瘫痪的遗传模拟物。
Mov Disord. 2019 May;34(5):625-636. doi: 10.1002/mds.27655. Epub 2019 Mar 26.
10
The complex aetiology of cerebral palsy.脑性瘫痪的复杂病因。
Nat Rev Neurol. 2018 Sep;14(9):528-543. doi: 10.1038/s41582-018-0043-6.