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Cell surface alterations in murine leukaemia P388 adriamycin-resistant cells: studies on lectin-induced agglutination and rearrangement of lectin receptors.

作者信息

Basrur V S, Chitnis M P, Menon R S

出版信息

Oncology. 1985;42(5):328-31. doi: 10.1159/000226055.

DOI:10.1159/000226055
PMID:4034147
Abstract

Cell surface alteration was studied in a subline of murine lymphocytic leukaemia resistant to the broad-spectrum anticancer agent adriamycin (P388/ADR) employing concanavalin A(Con A)-induced agglutination and rearrangement of lectin receptors. Con A induced more agglutination of P388/ADR when compared to the drug-sensitive parental cell line (P388/S). Studies on the redistribution of Con A and Ricinus communis agglutinin-I revealed a high percentage of P388/ADR showing internalized fluorescence, while a majority of P388/S displayed a uniform distribution of fluorescence on the cell surface.

摘要

相似文献

1
Cell surface alterations in murine leukaemia P388 adriamycin-resistant cells: studies on lectin-induced agglutination and rearrangement of lectin receptors.
Oncology. 1985;42(5):328-31. doi: 10.1159/000226055.
2
Differential agglutination of P388 adriamycin-sensitive and P388 adriamycin-resistant leukemia cells.
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引用本文的文献

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Increased plasma membrane traffic in daunorubicin resistant P388 leukaemic cells. Effect of daunorubicin and verapamil.柔红霉素耐药的P388白血病细胞中质膜转运增加。柔红霉素和维拉帕米的作用。
Br J Cancer. 1987 Dec;56(6):747-51. doi: 10.1038/bjc.1987.282.
2
A comparison of membrane properties and composition between cell lines selected and transfected for multi-drug resistance.对为多药耐药性而选择和转染的细胞系之间的膜特性和组成进行比较。
Br J Cancer. 1992 Nov;66(5):781-6. doi: 10.1038/bjc.1992.360.