Katran Zeynep Yegin, Bulut İsmet
University of Health Sciences, Süreyyapaşa Training and Research Hospital, Department of Allergy and Immunology;
University of Health Sciences, Süreyyapaşa Training and Research Hospital, Department of Allergy and Immunology.
Allergol Immunopathol (Madr). 2025 May 1;53(3):201-203. doi: 10.15586/aei.v53i3.1320. eCollection 2025.
Vitamin B12 (cobalamin) is a water-soluble vitamin that is derived from animal products such as red meat, dairy, and eggs. Cobalamin deficiency can be frequently seen in people all around the world. Desensitization is a treatment option if drug hypersensitivity develops and treatment is necessary. But intramuscular applications may cause treatment difficulties in such patients. A patient who developed cyanocobalamin deficiency due to pernicious anemia was shared. First, this patient was treated with cyanocobalamin. After treatment drug-induced hypersensitivity reaction developed. Desensitization was applied to the patient. Successful desensitization scheme was shared. Desensitization is of great value, as there are very limited treatment optıons in the literature on this subject, and it brings about a different option.
维生素B12（钴胺素）是一种水溶性维生素，来源于红肉、乳制品和蛋类等动物产品。钴胺素缺乏在世界各地的人群中都很常见。如果出现药物过敏且治疗必要，脱敏是一种治疗选择。但肌肉注射给药可能给这类患者带来治疗困难。分享了一名因恶性贫血导致钴胺素缺乏的患者案例。首先，该患者接受了钴胺素治疗。治疗后出现了药物性过敏反应。对该患者进行了脱敏治疗。分享了成功的脱敏方案。脱敏具有重要价值，因为关于这一主题的文献中治疗选择非常有限，而它带来了一种不同的选择。
