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[用一种新的光度法测定粪便中的糜蛋白酶]

[Determination of chymotrypsin in the feces by a new photometric method].

作者信息

Dockter G, Hoppe-Seyler F, Appel W, Sitzmann F C

出版信息

Padiatr Padol. 1985;20(3):257-65.

PMID:4034216
Abstract

Fecal chymotrypsin (FCT) was determined in stool specimens of healthy children and those with gastro-intestinal disease, by a new photometric method. The values are comparable with chymotrypsin concentrations found by pH-stat method. The new test is cheap, reliable and easy to perform. For this reasons and for the sensitivity of all tubeless pancreatic function tests (NBT-PABA, FDL, FCT) is rather low (60-70%), the FCT-test may be preferred as diagnostic marker for differential diagnosis of exocrine pancreatic insufficiency.

摘要

采用一种新的光度法测定了健康儿童和患有胃肠疾病儿童粪便标本中的粪糜蛋白酶(FCT)。其数值与通过pH计法测得的糜蛋白酶浓度具有可比性。这项新检测成本低、可靠且易于操作。由于所有无管胰腺功能检测(NBT - PABA、FDL、FCT)的敏感性都相当低(60 - 70%),FCT检测可能更适合作为诊断外分泌性胰腺功能不全的鉴别诊断标志物。

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