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Radiologic complete response after conversion therapy for hepatocellular carcinoma: is liver transplantation necessary?

作者信息

Gao Chen-Hao, Cao Lin Ping, Cheng Shu-Qun, Wang Lei, Wang Ji-Zhou, Yan Mao-Lin, Zheng Shu-Sen, Yang Zhe

机构信息

Department of Hepatobiliary and Pancreatic Surgery, Key Laboratory of Artificial Organs and Computational Medicine in Zhejiang Province, Shulan (Hangzhou) Hospital, Shulan International Medical College, Zhejiang Shuren University, Hangzhou, China.

Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

出版信息

Hepatobiliary Surg Nutr. 2025 Apr 1;14(2):351-354. doi: 10.21037/hbsn-2024-702. Epub 2025 Mar 21.

DOI:10.21037/hbsn-2024-702
PMID:40342783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12057504/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/094d/12057504/b8c3eef4674e/hbsn-14-02-351-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/094d/12057504/b8c3eef4674e/hbsn-14-02-351-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/094d/12057504/b8c3eef4674e/hbsn-14-02-351-f1.jpg

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1
Radiologic complete response after conversion therapy for hepatocellular carcinoma: is liver transplantation necessary?肝细胞癌转化治疗后的放射学完全缓解：是否需要肝移植？
Hepatobiliary Surg Nutr. 2025 Apr 1;14(2):351-354. doi: 10.21037/hbsn-2024-702. Epub 2025 Mar 21.
2
Association of Complete Radiologic and Pathologic Response following Locoregional Therapy before Liver Transplantation with Long-Term Outcomes of Hepatocellular Carcinoma: A Retrospective Study.肝移植前局部区域治疗后完全放射学和病理学反应与肝细胞癌长期预后的关联：一项回顾性研究
J Vasc Interv Radiol. 2019 Mar;30(3):323-329. doi: 10.1016/j.jvir.2018.11.037.
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Prediction of complete necrosis of hepatocellular carcinoma treated with transarterial chemoembolization prior to liver transplantation.预测经肝动脉化疗栓塞治疗后行肝移植的肝细胞癌完全坏死。
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Radiological appearance of hepatocellular carcinoma predicts the response to trans-arterial chemoembolization in patients undergoing liver transplantation.肝癌的放射学表现可预测行肝移植患者接受经动脉化疗栓塞治疗的反应。
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本文引用的文献

1
Watch-and-wait strategy vs. resection in patients with radiologic complete response after conversion therapy for initially unresectable hepatocellular carcinoma: a propensity score-matching comparative study.影像学完全缓解后转换治疗初不可切除的肝细胞癌患者的观察等待策略与切除术比较：倾向评分匹配的对比研究。
Int J Surg. 2024 May 1;110(5):2545-2555. doi: 10.1097/JS9.0000000000001155.
2
Outcomes of Salvage Surgery Versus Non-Salvage Surgery for Initially Unresectable Hepatocellular Carcinoma After Conversion Therapy with Transcatheter Arterial Chemoembolization Combined with Lenvatinib Plus Anti-PD-1 Antibody: A Multicenter Retrospective Study.经肝动脉化疗栓塞联合仑伐替尼加抗 PD-1 抗体转化治疗后初始不可切除的肝细胞癌行挽救性手术与非挽救性手术的疗效比较：一项多中心回顾性研究。
Ann Surg Oncol. 2024 May;31(5):3073-3083. doi: 10.1245/s10434-024-14944-3. Epub 2024 Feb 5.
3
Clinical Complete Response After Conversion Therapy for Unresectable Hepatocellular Carcinoma: Is Salvage Hepatectomy Necessary?不可切除肝细胞癌转化治疗后的临床完全缓解：是否需要挽救性肝切除术？
J Hepatocell Carcinoma. 2023 Dec 5;10:2161-2171. doi: 10.2147/JHC.S442341. eCollection 2023.
4
Survival benefit of liver resection following complete response to transarterial chemoembolization for intermediate-stage hepatocellular carcinoma: a retrospective, multicenter, cohort study.经肝动脉化疗栓塞术完全缓解后行肝切除术治疗中期肝细胞癌的生存获益：一项回顾性、多中心队列研究。
Int J Surg. 2024 Feb 1;110(2):1019-1027. doi: 10.1097/JS9.0000000000000942.
5
It's time to propose a uniform criteria for determining "clinical complete response" in hepatocellular carcinoma.现在是时候提出一套统一的标准来判定肝细胞癌的“临床完全缓解”了。
Hepatobiliary Surg Nutr. 2022 Aug;11(4):620-622. doi: 10.21037/hbsn-22-233.