Abdoli Sara, Gholami Amir Hossein, Masoumi Seyedeh Zahra, Najafi-Vosough Roya, Azimi Mozhdeh, Jenabi Ensiyeh, Aliabadi Sahar, Soltanian Ali Reza, Ghaleiha Ali, Pilehvari Shamim
Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran.
Malayer School of Medical Science, Hamadan University of Medical Sciences, Hamadan, Iran.
J Hum Reprod Sci. 2025 Jan-Mar;18(1):16-22. doi: 10.4103/jhrs.jhrs_168_24. Epub 2025 Mar 29.
The studies have shown that the effects of psychological distress on the outcome of fertilization (IVF) treatment are unclear, and there is still no conclusive empirical evidence that lower anxiety levels lead to better outcomes in assisted reproductive technique treatments.
the present study was conducted to investigate the impact of perceived anxiety and stress on the outcome of IVF in infertile women in Western Iran.
The current study is a cross-sectional study.
This study was conducted on infertile women who were candidates for IVF and visited the infertility center at Fatemiyeh Hospital in Hamadan City in the west of Iran from 8 July 2023, to 15 March 2024. The questionnaires were demographic and midwifery characteristics, the Spielberger State-Trait Anxiety Inventory and Perceived Stress Scale-14.
All statistical analyses were performed in SPSS software at a significance level of 0.05.
The stress was significantly associated with metaphase II eggs ( = -0.487), and the number of transferred embryos based on grade ( = -0.562), duration of marriage ( = 0.628), duration of infertility ( = 0.595) and duration of treatment ( = 0.595). There was no significant association between stress and endometrial thickness ( = 0.189). In addition, the anxiety was significantly associated with age ( = 0.509), husband›s age ( = 0.436), endometrial thickness ( = -0.173), metaphase II eggs ( = -0.570), and the number of transferred embryos based on grade ( = -0.610), duration of marriage ( = 0.604), duration of infertility ( = 0.592) and duration of treatment ( = 0.604).
Mean stress and anxiety in infertile women were significantly lower in infertile women with successful IVF. Stress was significantly associated with age, spouse's age, metaphase stage oocytes, embryo grade, duration of marriage and infertility and duration of treatment.
研究表明，心理困扰对体外受精（IVF）治疗结果的影响尚不清楚，目前仍没有确凿的实证证据表明较低的焦虑水平会在辅助生殖技术治疗中带来更好的结果。
本研究旨在调查伊朗西部不孕女性感知到的焦虑和压力对体外受精结果的影响。
本研究为横断面研究。
本研究针对2023年7月8日至2024年3月15日期间在伊朗西部哈马丹市法蒂米亚医院不孕中心就诊、符合体外受精条件的不孕女性展开。问卷内容包括人口统计学和助产特征、斯皮尔伯格状态-特质焦虑量表以及感知压力量表-14。
所有统计分析均在SPSS软件中进行，显著性水平设定为0.05。
压力与中期II级卵子（=-0.487）、根据等级划分的移植胚胎数量（=-0.562）、婚姻持续时间（=0.628）、不孕持续时间（=0.595）以及治疗持续时间（=0.595）显著相关。压力与子宫内膜厚度之间无显著关联（=0.189）。此外，焦虑与年龄（=0.509）、丈夫年龄（=0.436）、子宫内膜厚度（=-0.173）、中期II级卵子（=-0.570）、根据等级划分的移植胚胎数量（=-0.610）、婚姻持续时间（=0.604）、不孕持续时间（=0.592）以及治疗持续时间（=0.604）显著相关。
体外受精成功的不孕女性的平均压力和焦虑水平显著较低。压力与年龄、配偶年龄、中期卵母细胞阶段、胚胎等级、婚姻持续时间、不孕持续时间以及治疗持续时间显著相关。
