Riggs J E
Postgrad Med. 1985 Sep 1;78(3):217-26. doi: 10.1080/00325481.1985.11699126.
When adults present with muscle weakness as the predominant symptom and sign, the causes can usually be narrowed down to four disorders: amyotrophic lateral sclerosis, Guillain-Barré syndrome, myasthenia gravis, and inflammatory myopathy. Perhaps the most difficult task for the clinician is identifying which of these patients are actually weak and which are describing generalized fatigue. This task should be made easier by keeping in mind the definition of muscle weakness--a loss of power resulting in reduction of motor function--and by performing careful functional muscle testing.
当成年人以肌肉无力作为主要症状和体征出现时，病因通常可归结为四种疾病：肌萎缩侧索硬化症、吉兰 - 巴雷综合征、重症肌无力和炎性肌病。对于临床医生来说，最困难的任务或许是辨别哪些患者实际上存在肌肉无力，哪些只是在描述全身性疲劳。牢记肌肉无力的定义——导致运动功能减退的力量丧失——并进行仔细的功能性肌肉测试，这项任务应该会变得更容易。
