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整合技术以优化治疗效果:转移性髋臼周围病理性骨折的持久混合重建——病例报告

Integrating techniques to optimize outcomes: durable hybrid reconstruction of a metastatic periacetabular pathologic fracture - a case report.

作者信息

Shooroki Khalil Kargar, Khabiri Seyyed Saeed, Khodabakhshi Amirreza, Babaei Amirmohammad, Naghizadeh Hamed

机构信息

Bone and Joint Reconstruction Research Center, Department of Orthopedics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran; Bone and Joint Reconstruction Research Center, Department of Orthopedics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Int J Surg Case Rep. 2025 Jun;131:111408. doi: 10.1016/j.ijscr.2025.111408. Epub 2025 May 7.

DOI:10.1016/j.ijscr.2025.111408
PMID:40345049
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12138458/
Abstract

INTRODUCTION

Metastatic involvement of the periacetabular region is a rare but functionally devastating complication of advanced malignancies. Structural insufficiency fractures in this area lead to severe pain, loss of ambulation, and impaired quality of life. Surgical reconstruction is challenging due to poor bone quality, complex anatomy, and often prior radiotherapy.

CASE PRESENTATION

We report the case of a 36-year-old woman with a history of metastatic breast cancer who presented with acute right hip pain and inability to walk following a fall. Imaging revealed a metastatic insufficiency fracture of the right acetabulum involving the roof and both columns. The patient had a prior history of pelvic radiotherapy. A two-stage hybrid reconstruction was planned to optimize mechanical support while minimizing postoperative complications.

CLINICAL DISCUSSION

This case highlights the complexity of surgical decision-making in metastatic acetabular insufficiency. Various techniques exist, including cementoplasty, tripod fixation, Harrington reconstruction, 3D-printed implants, and pedestal prostheses. Each has unique advantages and limitations depending on lesion extent and patient factors. In our case, a staged hybrid approach (plate fixation, followed by Harrington + tripod + cemented THA) provided durable reconstruction without complications at 24 months follow-up.

CONCLUSION

Hybrid reconstruction offers a viable and effective option for managing complex metastatic periacetabular insufficiency fractures, particularly in previously irradiated patients. A multidisciplinary, staged strategy can achieve excellent functional outcomes with low complication rates.

摘要

引言

髋臼周围区域的转移累及是晚期恶性肿瘤罕见但功能严重受损的并发症。该区域的结构性不全骨折会导致严重疼痛、行走能力丧失和生活质量下降。由于骨质质量差、解剖结构复杂且常接受过放疗,手术重建具有挑战性。

病例报告

我们报告了一名36岁有转移性乳腺癌病史的女性病例,她因跌倒后出现急性右髋疼痛且无法行走。影像学检查显示右髋臼转移性不全骨折,累及髋臼顶和双侧髋臼柱。该患者既往有盆腔放疗史。计划进行两阶段混合重建,以优化机械支撑并减少术后并发症。

临床讨论

该病例突出了转移性髋臼不全手术决策的复杂性。存在多种技术,包括骨水泥成形术、三脚架固定、哈灵顿重建、3D打印植入物和基座假体。根据病变范围和患者因素,每种技术都有独特的优点和局限性。在我们的病例中,分阶段混合方法(钢板固定,随后进行哈灵顿 + 三脚架 + 骨水泥固定全髋关节置换术)在24个月的随访中提供了持久的重建且无并发症。

结论

混合重建为处理复杂的转移性髋臼周围不全骨折提供了一种可行且有效的选择,尤其是对于既往接受过放疗的患者。多学科分阶段策略可实现良好的功能结果且并发症发生率低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/12138458/eb3b47da89b2/gr7.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/12138458/eb3b47da89b2/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/12138458/1fa992a7a529/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/12138458/2c93ae4f15de/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/12138458/dd1752f1014c/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/12138458/077b927f2d99/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a6d/12138458/947204cfe835/gr5.jpg
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本文引用的文献

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Comparison of Percutaneous Techniques for Stabilization of Osteolytic Lesions of the Periacetabular Region Due to Metastatic Bone Disease.转移性骨病所致髋臼周围区域溶骨性病变稳定的经皮技术比较
Ann Surg Oncol. 2025 Mar;32(3):1529-1540. doi: 10.1245/s10434-024-16627-5. Epub 2024 Dec 4.
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Tripod-Fix device for the treatment of painful osteoporotic vertebral compression fractures.三脚固定装置治疗骨质疏松性椎体压缩性骨折引起的疼痛。
Sci Rep. 2024 Oct 12;14(1):23877. doi: 10.1038/s41598-024-75326-z.
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Biomechanical and clinical outcomes of 3D-printed versus modular hemipelvic prostheses for limb-salvage reconstruction following periacetabular tumor resection: a mid-term retrospective cohort study.
3D打印与模块化半骨盆假体用于髋臼周围肿瘤切除术后保肢重建的生物力学和临床结果:一项中期回顾性队列研究。
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Clinical efficacy analysis of percutaneous "tripod" combined with radiofrequency ablation and bone cement filling in the treatment of periacetabular metastases.经皮“三脚架”联合射频消融及骨水泥填充治疗髋臼周围转移瘤的临床疗效分析。
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