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一种冠状动脉治疗药物——心痛定的试验结果(作者译)

[Results of a trial of a coronary therapeutic agent, Adalat (author's transl)].

作者信息

Wildenhues M

出版信息

MMW Munch Med Wochenschr. 1977 Feb 18;119(7):233-4.

PMID:403451
Abstract

This report concerns data on 54 patients with coronary heart disease. With a 4-6 week treatment with 3 X 1 capsule Adalat daily, the attacks of angina pectoris fell from 1-7 daily to 1-2 per week. In more than 50% of the subjects, no more attacks occurred. Nitroglycerine consumption fell accordingly. Ergometry carried out on 12 patients at the end of the study showed an increased load resistance of 20 to 30 W in each case, compared with the initial value. The preparation was well tolerated.

摘要

本报告涉及54例冠心病患者的数据。每日服用3次,每次1粒拜新同,治疗4 - 6周后,心绞痛发作次数从每天1 - 7次降至每周1 - 2次。超过50%的受试者不再发作。硝酸甘油的消耗量也相应减少。研究结束时对12例患者进行的运动试验显示,与初始值相比,每例患者的负荷耐力均增加了20至30瓦。该制剂耐受性良好。

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