Testerini Federica Barbara Beatrice, Gramegna Federica, Denti Paolo, Bragato Renato Maria, Agricola Eustachio, Presbitero Patrizia, Condorelli Gianluigi, Maisano Francesco
Department of Biomedical Science, Humanitas University, Pieve Emanuele, Italy; Department of Clinical and Interventional Cardiology, IRCCS Istituto Clinico Humanitas, Rozzano, Italy.
Vita-Salute San Raffaele University, Milano, Italy; Department of Cardiac surgery, IRCCS Ospedale Universitario San Raffaele, Milano, Italy.
JACC Case Rep. 2025 May 7;30(9):103272. doi: 10.1016/j.jaccas.2025.103272. Epub 2025 Mar 12.
A 60-year-old woman with tricuspid atresia had previously undergone palliation with a Glenn procedure and a Blalock-Taussig shunt, and finally correction with a Fontan procedure. Twenty-five years later, severe atrioventricular valve regurgitation with concomitant valvular prolapse and cleft leading to heart failure was successfully treated using 1 single MitraClip XTW, confirming its effectiveness as a lower-risk alternative to surgery. The patient showed marked improvement of heart failure-related symptoms, with residual mild to moderate regurgitation and improved liver function.
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