Sumal Anoop S, Kyriacou Harry, Mostafa Ahmed M H A M
School of Clinical Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
J Card Surg. 2020 Jul;35(7):1609-1617. doi: 10.1111/jocs.14673. Epub 2020 Jun 2.
Tricuspid atresia (TA) is a complex congenital heart disease that presents with cyanosis in the neonatal period. It is invariably fatal if left untreated and requires multiple stages of palliation. Early recognition and timely surgical intervention are therefore pivotal in the management of these infants. This literature review considers the pathophysiology, presentation, investigations, and classification of TA. Moreover, it discusses the evidence upon which the latest medical and surgical treatments are based, as well as numerous recent case reports. Further work is needed to elucidate the etiology of TA, clarify the role of pharmacotherapy, and optimize the surgical management that these patients receive.
三尖瓣闭锁（TA）是一种复杂的先天性心脏病，在新生儿期即出现青紫。若不治疗，必然致命，需要多阶段的姑息治疗。因此，早期识别和及时的手术干预对这些婴儿的治疗至关重要。这篇文献综述探讨了三尖瓣闭锁的病理生理学、临床表现、检查及分类。此外，还讨论了最新药物和手术治疗所依据的证据，以及众多近期的病例报告。还需要进一步开展工作以阐明三尖瓣闭锁的病因，明确药物治疗的作用，并优化这些患者接受的手术治疗。
