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妊娠期高血压疾病的诊断

Diagnosis of hypertensive disorders in pregnancy.

作者信息

Horgan Rebecca, Hage Diab Yara, Costantine Maged, Saade George, Sibai Baha

机构信息

Department of Obstetrics and Gynecology, Macon & Joan Brock Virginia Health Sciences, Old Dominion University, Norfolk, VA (Horgan, Diab, and Saade).

Department of Obstetrics and Gynecology, Macon & Joan Brock Virginia Health Sciences, Old Dominion University, Norfolk, VA (Horgan, Diab, and Saade).

出版信息

Am J Obstet Gynecol MFM. 2025 Jul;7(7):101693. doi: 10.1016/j.ajogmf.2025.101693. Epub 2025 May 8.

DOI:10.1016/j.ajogmf.2025.101693
PMID:40348190
Abstract

Hypertensive disorders of pregnancy, including chronic hypertension (CHTN), superimposed preeclampsia, gestational hypertension, and preeclampsia, affect 10% to 20% of pregnancies and are a significant cause of maternal and perinatal morbidity and mortality. The incidence of these disorders is increasing because of factors, such as advanced maternal age, obesity, assisted reproductive technology, and increased rates of preexisting comorbidities. Differentiating pregnancy-associated hypertension from preexisting CHTN is challenging, as the overlap between the 2 may be broadening because of the changing demographics of the pregnant population. This review critically evaluated the evidence regarding the current periods recommended to make a diagnosis of a hypertensive disorder of pregnancy. This review does not provide evidence to support the arbitrary 4-hour period or any particular period for the diagnosis of hypertensive disorders in pregnancy. In addition, there is no clear definition of what is considered persistent or sustained blood pressure elevations in blood pressure. Every effort should be made to ensure accurate diagnosis of new-onset elevated blood pressures during pregnancy before labeling the patient with the diagnosis and, thus, recommending serial maternal and fetal testing and delivery at or before 37 weeks of gestation.

摘要

妊娠高血压疾病,包括慢性高血压(CHTN)、子痫前期叠加征、妊娠期高血压和子痫前期,影响10%至20%的妊娠,是孕产妇和围产儿发病和死亡的重要原因。由于诸如高龄孕产妇、肥胖、辅助生殖技术以及既往合并症发生率增加等因素,这些疾病的发病率正在上升。区分妊娠相关高血压与既往存在的CHTN具有挑战性,因为由于孕妇人群人口统计学特征的变化,两者之间的重叠可能正在扩大。本综述批判性地评估了有关目前推荐用于诊断妊娠高血压疾病的时间段的证据。本综述未提供证据支持用于诊断妊娠高血压疾病的任意4小时时间段或任何特定时间段。此外,对于血压持续或持续升高的定义尚无明确界定。应尽一切努力确保在给患者贴上诊断标签之前准确诊断孕期新发血压升高,从而建议进行系列母胎检查并在妊娠37周或之前分娩。

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BMC Pregnancy Childbirth. 2025 Sep 2;25(1):923. doi: 10.1186/s12884-025-08006-z.