神经肌肉阻滞剂与支气管镜检查术后肺部并发症的关联：定义方面的挑战
Association of neuromuscular reversal drug with postoperative pulmonary complications in bronchoscopy: definitional challenges.
作者信息
Colquhoun Douglas A, Fernandez-Bustamante Ana
机构信息
Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, USA.
Department of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
出版信息
Br J Anaesth. 2025 Jul;135(1):17-20. doi: 10.1016/j.bja.2025.04.005. Epub 2025 May 9.
Abstract
A recent retrospective study examined a composite of postoperative pulmonary complications after neostigmine or sugammadex for reversal of neuromuscular block in patients undergoing interventional pulmonology and bronchoscopic procedures. This study reviewed the electronic medical records of 8557 patients across hospitals within a single health system, finding an increased risk of a composite of postoperative pulmonary complications in those receiving sugammadex (odds ratio 1.44; 95% confidence interval: 1.02-2.05). We discuss the challenge of interpreting conflicting findings in the contemporary perioperative literature arising from heterogeneous definitions of postoperative pulmonary complications.
摘要
最近一项回顾性研究，调查了新斯的明或舒更葡糖用于逆转介入肺科和支气管镜检查患者的神经肌肉阻滞之后的术后肺部并发症综合情况。该研究回顾了单一医疗系统内各医院8557例患者的电子病历，发现接受舒更葡糖的患者出现术后肺部并发症综合情况的风险增加（比值比1.44；95%置信区间：1.02 - 2.05）。我们讨论了当代围手术期文献中，由于术后肺部并发症定义不统一而导致相互矛盾的研究结果的解读难题。
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本文引用的文献
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Br J Anaesth. 2025 Jul;135(1):197-205. doi: 10.1016/j.bja.2025.01.039. Epub 2025 Mar 14.
2
Perioperative lung expansion and pulmonary outcomes after open abdominal surgery versus usual care in the USA (PRIME-AIR): a multicentre, randomised, controlled, phase 3 trial.美国开放性腹部手术围手术期肺扩张与肺部结局对比常规护理（PRIME-AIR）：一项多中心、随机、对照、3期试验。
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