Disma Nicola, Habre Walid
Unit for Research in Anaesthesia, IRCCS Istituto Giannina Gaslini, Genova, Italy.
Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA.
Br J Anaesth. 2025 Jul;135(1):14-16. doi: 10.1016/j.bja.2025.04.006. Epub 2025 May 9.
A large international prospective pragmatic study (EUROFAST), analysing more than 306 900 anaesthetic procedures across 31 centres, compared the incidence of pulmonary aspiration in children after three different clear fluid fasting regimens: traditional fasting (≥2 h before induction of anaesthesia), ≥1 h fasting before induction and sip-til-send. EUROFAST provided further evidence supporting the safety of liberal fasting times by demonstrating that the incidence of confirmed pulmonary aspiration with fasting durations of ≥1 h is not higher than that observed with a ≥2 h fasting period. EUROFAST provided additional evidence to support changes in practice for institutions that still adhere to the outdated 6-4-2 fasting regimen by adopting a more modern approach of ≥1 h fasting or sip-til-send.
一项大型国际前瞻性实用研究(EUROFAST)分析了31个中心的306900多例麻醉手术,比较了三种不同清液禁食方案后儿童肺误吸的发生率:传统禁食(麻醉诱导前≥2小时)、诱导前≥1小时禁食和“啜饮至送走”。EUROFAST通过证明禁食时间≥1小时时确诊肺误吸的发生率不高于禁食≥2小时时观察到的发生率,提供了进一步证据支持放宽禁食时间的安全性。EUROFAST提供了更多证据,支持那些仍坚持过时的6-4-2禁食方案的机构通过采用≥1小时禁食或“啜饮至送走”这种更现代的方法来改变做法。