Beltrán Jacqueline M, Jacob Yael, Mehta Marishka M, Hossain Tasnim, Adams Abigail, Fontaine Samantha, Torous John, McDonough Catherine, Johnson Matthew, Delgado Andrew D, Murrough James W, Morris Laurel S
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Nash Family Department of Neuroscience & Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
NPJ Digit Med. 2025 May 10;8(1):268. doi: 10.1038/s41746-025-01669-0.
Mood and anxiety disorders are highly comorbid, with symptom severity varying over time. Individuals with and without these disorders completed 30-days of ecological momentary assessment (EMAs) of depression, anxiety and distress, developed based on the established Mood and Anxiety Symptom Questionnaire (MASQ). These electronic MASQ (eMASQ) EMAs were collected alongside novel intrinsic and extrinsic motivation EMAs, and physical/digital activity measures (steps/screentime) across N = 70-101 participants. Each eMASQ-EMA significantly related to its corresponding MASQ measure. Extrinsic and intrinsic motivation negatively related to each eMASQ-EMA and had the greatest influence on patients' overall symptom profile. Physical, but not digital activity, was negatively associated with concurrent and 1-week lagged anxiety and depression, highlighting the temporally delayed benefits of physical activity on depression and anxiety symptoms in psychiatric groups. Collectively, this study suggests cognitive constructs related to drive and physical activity, may be useful in predicting continuous and transient psychiatric symptoms in the real-world.
情绪和焦虑障碍高度共病，症状严重程度随时间变化。患有和未患有这些障碍的个体完成了基于既定的情绪和焦虑症状问卷（MASQ）开发的为期30天的抑郁、焦虑和痛苦的生态瞬时评估（EMA）。这些电子MASQ（eMASQ）EMA是与新的内在和外在动机EMA以及N = 70 - 101名参与者的身体/数字活动测量（步数/屏幕时间）一起收集的。每个eMASQ - EMA与其相应的MASQ测量显著相关。外在和内在动机与每个eMASQ - EMA呈负相关，并且对患者的整体症状概况影响最大。身体活动而非数字活动与同时期和滞后1周的焦虑和抑郁呈负相关，突出了身体活动对精神疾病群体中抑郁和焦虑症状的时间延迟益处。总体而言，这项研究表明，与驱动力和身体活动相关的认知结构可能有助于预测现实世界中持续和短暂的精神症状。
